Qualità delle meta-analisi in Gastroenterologia ed Epatologia
- Categoria: Metodologia
Quality of Meta-analyses in Major Leading Gastroenterology and Hepatology Journals: A Systematic Review.Liu P1, Qiu Y, Qian Y, Chen X, Wang Y, Cui J, Zhai X. Gastroenterol Hepatol. 2016 Sep 6. [Epub ahead of print]
BACKGROUND AND AIM:To appraise the current reporting methodological quality of meta-analyses in five leading gastroenterology and hepatology journals, and to identify the variables associated with the reporting quality.METHODS:We systematically searched the literature of meta-analyses in Gastroenterology, Gut, Hepatology, Journal of Hepatology (J HEPATOL) and American Journal of Gastroenterology (AM J GASTROENTEROL) from 2006 to 2008 and from 2012 to 2014.
Cicli ripetuti di rifaximina sono efficaci e sicuri nel trattamento dell’IBS-D
- Categoria: Gastroenterologia
Repeat Treatment With Rifaximin is Safe and Effective in Patients With Diarrhea-predominant Irritable Bowel Syndrome.Lembo A, Pimentel M, Rao SS, Schoenfeld P, Cash B, Weinstock LB, Paterson C, Bortey E, Forbes WP. Gastroenterology. 2016 content Aug 12 [Epub ahead of print]
BACKGROUND AND AIMS:Few treatments have demonstrated efficacy and safety for diarrhea-predominant irritable bowel syndrome (IBS-D). A phase 3, randomized, double-blind, placebo-controlled trial was performed to evaluate the safety and efficacy of repeat treatment with the nonsystemic antibiotic rifaximin.
Consenso informato in endoscopia
- Categoria: Linee guida
Guideline for obtaining valid consent for gastrointestinal endoscopy procedures. Simon M Everett, Helen Griffiths, U Nandasoma, Katie Ayres, Graham Bell, Mike Cohen, Siwan Thomas-Gibson, Mike Thomson, Kevin M T Naylor .Gut 2016;65:1585-1601
Much has changed since the last guideline of 2008, both in endoscopy and in the practice of obtaining informed consent, and it is vital that all endoscopists who are responsible for performing invasive and increasingly risky procedures are aware of the requirements for obtaining valid consent.
FUSE non migliora ADR
- Categoria: Endoscopia
Full-spectrum (FUSE) versus standard forward-viewing colonoscopy in an organised colorectal cancer screening programme.Hassan C, Senore C, Radaelli F, De Pretis G, Sassatelli R, Arrigoni A, Manes G, Amato A, Anderloni A, Armelao F, Mondardini A, Spada C, Omazzi B, Cavina M, Miori G, Campanale C, Sereni G, Segnan N, Repici A. Gut. 2016 Aug 9. [Epub ahead of print]
OBJECTIVE:Miss rate of polyps has been shown to be substantially lower with full-spectrum endoscopy (FUSE) compared with standard forward-viewing (SFV) colonoscopy in a tandem study at per polyp analysis. However, there is uncertainty on whether FUSE is also associated with a higher detection rate of colorectal neoplasia, especially advanced lesions, in per patient analysis.
FMT efficace nell’infezione ricorrente
- Categoria: Gastroenterologia
Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial.Kelly CR, Khoruts A, Staley C, Sadowsky MJ, Abd M, Alani M, Bakow B, Curran P, McKenney J, Tisch A, Reinert SE, Machan JT, Brandt LJ. Ann Intern Med. 2016 Aug 23. doi: 10.7326/M16-0271. [Epub ahead of print]
Background:To date, evidence for the efficacy of fecal microbiota transplantation (FMT) in recurrent Clostridium difficile infection (CDI) has been limited to case series and open-label clinical trials.Objective:To determine the efficacy and safety of FMT for treatment of recurrent CDI.