Colonscopia è associata a rischio di appendicite

Association of Colonoscopy With Risk of Appendicitis.Basson MD, Persinger D, Newman WP. JAMA Surg. 2017 Oct 4. [Epub ahead of print]

Appendicitis can occur after a patient undergoes a colonoscopy,1 but because both are common, it is unclear whether a colonoscopy increases appendicitis risk. We hypothesized that patients develop appendicitis more frequently within 1 week after undergoing a colonoscopy than during the following 51 weeks.

After obtaining approval and a waiver of informed consent from the University of North Dakota and Fargo Veterans Affairs Medical Center institutional review boards, we identified 392 485 veterans from US Department of Veterans Affairs administrative data with a screening colonoscopy Current Procedural Terminology (CPT) code between January 2009 and June 2014, excluding sigmoidoscopy or incomplete colonoscopy codes. We sought over the following year a CPT code for appendectomy, an International Classification of Diseases, Ninth Revision (ICD-9) code for appendicitis, both CPT and ICD-9 codes, or the appendectomy CPT code with a discharge diagnosis of appendicitis. We calculated the incidence rate ratio (IRR) for appendicitis within 1 week after undergoing a colonoscopy and for the following 51 weeks. χ2 Statistics and 95% confidence intervals were calculated.

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