Review sistematica sulla chirurgia bariatrica

Gastric banding or bypass? A systematic review comparing the two most popular bariatric procedures.Tice JA, Karliner L, Walsh J, Petersen AJ, Feldman MD. Am J Med. 2008 Oct;121(10):885-93. OBJECTIVE: Bariatric surgical procedures have increased exponentially in the United States. Laparoscopic adjustable gastric banding is now promoted as a safer, potentially reversible and effective alternative to…

Le statine riducono la mortalità in pazienti con polmonite

Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients.Thomsen RW, Riis A, Kornum JB, Christensen S, Johnsen SP, Sørensen HT. Arch Intern Med. 2008 Oct 27;168(19):2081-7.  BACKGROUND: While some experimental and clinical research suggests that statins improve outcomes after severe infections, the evidence for pneumonia is conflicting. We examined…

Antidepressivi e psicoterapia nell’IBS: una review sistematica

Efficacy of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: Systematic Review and Meta-analysis.Ford AC, Talley NJ, Schoenfeld PS, Quigley EM, Moayyedi P. Gut. 2008 Nov 10. [Epub ahead of print]   OBJECTIVE: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence for treatment of the condition with antidepressants and psychological therapies is…

Pioglitazone nella NASH: un RCT

Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis.Aithal GP, Thomas JA, Kaye PV, Lawson A, Ryder SD, Spendlove I, Austin AS, Freeman JG, Morgan L, Webber J. Gastroenterology. 2008 Oct;135(4):1176-84 BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease for which there is limited therapy available. Insulin sensitizing,…