Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis.Salerno F, Gerbes A, Gin?s P, Wong F, Arroyo V. Gut. 2007 Sep;56(9):1310-8.
Hepatorenal syndrome (HRS) is a serious complication of end-stage liver disease, occurring mainly in patients with advanced cirrhosis and ascites, who have marked circulatory dysfunction, as well as in patients with acute liver failure. In spite of its functional nature, HRS is associated with a poor prognosis.and the only effective treatment is liver transplantation. During the 56th Meeting of the American Association for the Study of Liver Diseases, the International Ascites Club held a Focused Study Group (FSG) on HRS for the purpose of reporting the results of an international workshop and to reach a consensus on a new definition, criteria for diagnosis and recommendations on HRS treatment. A similar workshop was held in Chicago in 1994 in which standardised nomenclature and diagnostic criteria for refractory ascites and HRS were established. The introduction of innovative treatments and improvements in our understanding of the pathogenesis of HRS during the previous . . .