Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive .Roman Jaeschke, Gordon H Guyatt, Phil Dellinger, Holger Schünemann, Mitchell M Levy, Regina Kunz, Susan Norris, Julian Bion for the GRADE working group.BMJ 2008 337: a744
Guidelines have become an important vehicle for influencing clinical practice. Many local, national, and international societies now go through the process of identifying relevant clinical areas, formulating specific clinical questions, reviewing the applicable evidence, and formulating recommendations that they believe clinicians and their patients should follow.
Over the years, in recognition of the diversity of individuals required to produce optimal recommendations (content experts, methodologists, front line clinicians, patients’ representatives), guideline panels have grown in size. The resulting large and diverse panels present challenges for decision making, such as ensuring that all participants have a voice and can influence the results of the debate, ensuring transparency, dealing with disagreement, achieving consensus, and resolving situations in which consensus is not possible. Guideline panels often use only informal processes to deal with these challenges. Informal processes are, however, vulnerable to the idiosyncrasies of small or moderate sized group interaction. Factors including time pressure; . . .Leggi l’articolo