Clopidogrel + PPI :impatto sull’outcome e mortalità cardiovascolare

Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Rassen JA, Choudhry NK, Avorn J, Schneeweiss S. Circulation. 2009 Dec 8;120(23):2322-9.   BACKGROUND: Recent studies have raised concerns about the reduced efficacy of clopidogrel when used concurrently with proton pump inhibitors (PPIs), but those studies…