Validazione dell’ ABCD2 score per predire il rischio di ictus dopo TIA

Multicenter external validation of the ABCD2 score in triaging TIA patients.Tsivgoulis G, Stamboulis E, Sharma VK, Heliopoulos I, Voumvourakis K, Teoh HL, Patousi A, Andrikopoulou A, Lim EL, Stilou L, Sim TB, Chan BP, Stefanis L, Vadikolias K, Piperidou C. Neurology. 2010 Apr 27;74(17):1351-7.  OBJECTIVES: A simple clinical score (ABCD(2) score) has been introduced to triage…

Sigmodoscopia per screening CCR: un RCT con FU superiore a 10 anni

Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial. Atkin WS, Edwards R, Kralj-Hans I, Wooldrage K, Hart AR, Northover JM, Parkin DM, Wardle J, Duffy SW, Cuzick J; UK Flexible Sigmoidoscopy Trial Investigators. Lancet. 2010 May 8;375(9726):1624-33.    BACKGROUND: Colorectal cancer is the third most common cancer worldwide and has…

Prevenzione e controllo delle epatiti B e C

Institute of Medicine recommendations for the prevention and control of hepatitis B and C.Mitchell AE, Colvin HM, Palmer Beasley R. Hepatology. 2010 Mar;51(3):729-33.  Despite federal, state, and local public health efforts to prevent and control hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, these diseases remain serious health problems in the United States. About…

Terapia neoadiuvante nel k pancreas : un RCT

Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study.Colucci G, Labianca R, Di Costanzo F, Gebbia V, Cartenì G, Massidda B, Dapretto E, Manzione L, Piazza E, Sannicolò M, Ciaparrone M, Cavanna L, Giuliani F, Maiello E, Testa A, Pederzoli…