Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease.Petersen KF, Dufour S, Hariri A, Nelson-Williams C, Foo JN, Zhang XM, Dziura J, Lifton RP, Shulman GI. N Engl J Med. 2010 Mar 25;362(12):1082-9. BACKGROUND: Nonalcoholic fatty liver disease is associated with hepatic insulin resistance and type 2 diabetes mellitus. Whether this association has a genetic basis…
Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study. Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, Daugherty JR, Kaltenbach LA, Stein CM. Ann Intern Med. 2010 Mar 16;152(6):337-45. BACKGROUND: Proton-pump inhibitors (PPIs) and clopidogrel are frequently coprescribed, although the benefits and harms of their concurrent use are unclear.…
Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies.Larsson SC, Orsini N, Wolk A. JAMA. 2010 Mar 17;303(11):1077-83. CONTEXT: Mounting evidence indicates that vitamin B(6), a coenzyme involved in nearly 100 enzymatic reactions, may reduce the risk of colorectal cancer.
Clinical outcomes of radiofrequency ablation, percutaneous alcohol and acetic acid injection for hepatocelullar carcinoma: A meta-analysis.Germani G, Pleguezuelo M, Gurusamy K, Meyer T, Isgrò G, Burroughs AK. J Hepatol. 2010 Jan 17. [Epub ahead of print] BACKGROUND & AIMS: Radiofrequency ablation (RFA) is often the preferred local ablation therapy for hepatocellular carcinoma (HCC). Percutaneous ethanol injection…
Diagnosis and management of primary sclerosing cholangitis.Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ; American Association for the Study of Liver Diseases. Hepatology. 2010 Feb;51(2):660-78. leggi l’articolo
Long-term quality of life after radiotherapy for the treatment of anal cancer.Das P, Cantor SB, Parker CL, Zampieri JB, Baschnagel A, Eng C, Delclos ME, Krishnan S, Janjan NA, Crane CH. Cancer. 2010 Feb 15;116(4):822-9. BACKGROUND: Radiotherapy is the current standard of care for patients with localized squamous cell cancer of the anal canal. The goal…