Contrasting US and European approaches to colorectal cancer screening: which is best?Hoff G, Dominitz JA. Gut. 2010 Mar;59(3):407-14. In the recent 1-2 decades, we have seen a considerable development in colorectal cancer (CRC) screening modalities and programme implementation, but major challenges remain.
Combined endoscopic and percutaneous drainage of organized pancreatic necrosis.Ross A, Gluck M, Irani S, Hauptmann E, Fotoohi M, Siegal J, Robinson D, Crane R, Kozarek R. Gastrointest Endosc. 2010 Jan;71(1):79-84. Epub 2009 Oct 27. BACKGROUND: Severe acute pancreatitis is often complicated by organized necrosis, which can lead to abscess formation and clinical deterioration. We sought to…
A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends.Meddings L, Myers RP, Hubbard J, Shaheen AA, Laupland KB, Dixon E, Coffin C, Kaplan GG. Am J Gastroenterol. 2010 Jan;105(1):117-24. Epub 2009 Nov 3.OBJECTIVES: Few population-based studies have evaluated pyogenic liver abscess (PLA) in North America. We assessed the…
Inflammatory bowel disease confers a lower risk of colorectal cancer to females than to males.Söderlund S, Granath F, Broström O, Karlén P, Löfberg R, Ekbom A, Askling J. Gastroenterology. 2010 Feb 15. [Epub ahead of print] BACKGROUND & AIMS: Reported differences in cancer risk between male and female animals following chronic inflammation suggest that estrogen has…
Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma. Lencioni R, Llovet JM. Semin Liver Dis. 2010 Feb;30(1):52-60. The endpoint in cancer research is overall survival. Nonetheless, other potential surrogate endpoints, such as response rate and time to progression, are currently used. Measurement of response rate in hepatocellular carcinoma (HCC) has become a controversial issue.
Rifaximin treatment in hepatic encephalopathy.Bass NM, Mullen KD, Sanyal A, Poordad F, Neff G, Leevy CB, Sigal S, Sheikh MY, Beavers K, Frederick T, Teperman L, Hillebrand D, Huang S, Merchant K, Shaw A, Bortey E, Forbes WP. N Engl J Med. 2010 Mar 25;362(12):1071-81. BACKGROUND: Hepatic encephalopathy is a chronically debilitating complication of hepatic cirrhosis.…