Trattamento chirurgico degli adenomi epatici

A single-center surgical experience of 122  patients with single and multiple hepatocellular adenomas.  Dokmak S, Paradis V, Vilgrain V, Sauvanet A, Farges O, Valla D, Bedossa P, Belghiti J. Gastroenterology. 2009 Nov;137(5):1698-705.  BACKGROUND & AIMS: Hepatocellular adenoma (HA) is associated with risk of bleeding and malignancy, justifying resection. Patients with multiple forms of HA are…

Infliximab preoperatorio e rischio di complicanze post-operatorie

Meta-analysis: preoperative infliximab treatment and short-term postoperative complications in patients with ulcerative colitis. Yang Z, Wu Q, Wu K, Fan D. Aliment Pharmacol Ther. 2009 Nov 19. [Epub ahead of print]  Background: Infliximab was approved for use in ulcerative colitis (UC) in recent years. It has been debated if infliximab increases the risk of postoperative complications…

Rischio di sanguinamento aumentato in corso di terapia combinata : aspirina+clopidogrel

Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data.Sørensen R, Hansen ML, Abildstrom SZ, Hvelplund A, Andersson C, Jørgensen C, Madsen JK, Hansen PR, Køber L, Torp-Pedersen C, Gislason GH. Lancet. 2009 Dec 12;374(9706):1967-74. BACKGROUND: Combinations…

Review sul management dell’HCC

Review article: management of hepatocellular carcinoma.Cabrera R, Nelson DR. Aliment Pharmacol Ther. 2009 Nov 19. [Epub ahead of print]  Background Hepatocellular carcinoma (HCC) is the leading cause of death in cirrhosis. The majority of patients present at an advanced stage with poor prognosis. Aims To review the current screening, diagnosis, and management strategies involved in HCC.

Prevenzione delle infezioni postchirurgiche

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH.N Engl J Med. 2010 Jan 7;362(1):18-26. BACKGROUND: Since the patient’s skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis…