MAP e rischio di tumori extracolonici

Expanded extracolonic tumor spectrum in MUTYH-associated polyposis.Vogt S, Jones N, Christian D, Engel C, Nielsen M, Kaufmann A, Steinke V, Vasen HF, Propping P, Sampson JR, Hes FJ, Aretz S. Gastroenterology. 2009 Dec;137(6):1976-85.e1-10. Epub 2009 Sep 2. BACKGROUND & AIMS: MUTYH-associated polyposis (MAP) is characterized by a lifetime risk of colorectal cancer of up to 100%.…

Review sull’epatite delta

Epidemiology, pathogenesis and management of hepatitis D: update and challenges ahead. Wedemeyer H, Manns MP. Nat Rev Gastroenterol Hepatol. 2010 Jan;7(1):31-40. Hepatitis D is caused by infection with the hepatitis D virus (HDV) and is considered to be the most severe form of viral hepatitis in humans. Hepatitis D occurs only in individuals positive for the…

Lanreotide nel trattamento del fegato policistico

Lanreotide reduces the volume of polycystic liver: a randomized, double-blind, placebo-controlled trial. van Keimpema L, Nevens F, Vanslembrouck R, van Oijen MG, Hoffmann AL, Dekker HM, de Man RA, Drenth JP. Gastroenterology. 2009 Nov;137(5):1661-8.e1-2.  BACKGROUND & AIMS: Therapy for polycystic liver is invasive, expensive, and has disappointing long-term results. Treatment with somatostatin analogues slowed kidney…

Implicazioni cliniche della guarigione mucosa nel management delle IBD

 Clinical implications of mucosal healing for the management of IBD.Pineton de Chambrun G, Peyrin-Biroulet L, Lémann M, Colombel JF. Nat Rev Gastroenterol Hepatol. 2010 Jan;7(1):15-29. Epub 2009 Dec 1.  Mucosal healing (MH) has emerged as an important treatment goal for patients with IBD. Historically, the therapeutic goals of induction and maintenance of clinical remission seemed insufficient…

Caffè riduce rischio di HCC

Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C.Freedman ND, Everhart JE, Lindsay KL, Ghany MG, Curto TM, Shiffman ML, Lee WM, Lok AS, Di Bisceglie AM, Bonkovsky HL, Hoefs JC, Dienstag JL, Morishima C, Abnet CC, Sinha R; HALT-C Trial Group. Hepatology. 2009 Nov;50(5):1360-9. Higher coffee consumption has been…