Necessario ridurre la variabilità del limite superiore di normalità delle transaminasi

Variability in the upper limit of normal for serum alanine aminotransferase levels: a statewide study. Dutta A, Saha C, Johnson CS, Chalasani N. Hepatology. 2009 Dec;50(6):1957-62. We conducted a study to characterize the variability in the upper limit of normal (ULN) for alanine aminotransferase (ALT) across different laboratories (labs) in Indiana and to understand factors leading…

Review sistematica sul trattamento delle metastasi epatiche da K colon

Systematic review of tumour number and outcome after radical treatment of colorectal liver metastases.Smith MD, McCall JL. Br J Surg. 2009 Oct;96(10):1101-13.  BACKGROUND: Resection of colorectal liver metastases (CLMs) is potentially curative but the effect of tumour number on prognosis is uncertain. This study compared the prognosis after resection and/or ablation of between one and three,…

Review sistematica sulla pentossifilina nell’ epatite alcolica

Pentoxifylline for alcoholic hepatitis.Whitfield K, Rambaldi A, Wetterslev J, Gluud C. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007339. BACKGROUND: Alcoholic hepatitis is a life-threatening disease, with an average mortality of approximately 40%. There is no widely accepted, effective treatment for alcoholic hepatitis. Pentoxifylline is used to treat alcoholic hepatitis, but there has been no systematic review…