Statine riducono rischio di calcoli

Statin use and risk of gallstone disease followed by cholecystectomy.Bodmer M, Brauchli YB, Krähenbühl S, Jick SS, Meier CR. JAMA. 2009 Nov 11;302(18):2001-7. CONTEXT: Gallstone disease is a leading cause of morbidity in western countries and carries a high economic burden. Statins decrease hepatic cholesterol biosynthesis and may therefore lower the risk of cholesterol gallstones by…

Errori nel condurre review sistematiche sulla terapia dell’IBS

Errors in the Conduct of Systematic Reviews of Pharmacological Interventions for Irritable Bowel Syndrome.Ford AC, Guyatt GH, Talley NJ, Moayyedi P. Am J Gastroenterol. 2009 Nov 17. [Epub ahead of print]  OBJECTIVES:Systematic reviews and meta-analyses are integral to evidence-based clinical decision making. Although flawed systematic reviews could compromise optimal decision making, their accuracy has received limited…