Is earlier referral and investigation of bowel cancer patients presenting with rectal bleeding associated with better survival?M R Thompson, A Asiimwe, K G Flashman, G Tsavellas. Colorectal Disease Accepted manuscript online: 30 SEP 2010Aim: The study was carried out to determine whether rectal bleeding is related to stage of bowel cancer and whether earlier diagnosis…
An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response.Mangia A, Thompson AJ, Santoro R, Piazzolla V, Tillmann HL, Patel K, Shianna KV, Mottola L, Petruzzellis D, Bacca D, Carretta V, Minerva N, Goldstein DB, McHutchison JG. Gastroenterology. 2010 Sep;139(3):821-7, 827.e1. Epub…
Systematic review: granulocyte/monocyte adsorptive apheresis for ulcerative colitisS. Thanaraj, P. J. Hamlin, A. C. Ford. Alimentary Pharmacology & TherapeuticsArticle first published online: 14 OCT 2010 Background Patients with ulcerative colitis (UC) that is chronically active despite 5-aminosalicylates or immunomodulators, or who are dependent on corticosteroids to maintain remission, have limited treatment options. Granulocyte/monocyte adsorptive apheresis (GMAA)…
Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis.Kumar A, Zarychanski R, Light B, Parrillo J, Maki D, Simon D, Laporta D, Lapinsky S, Ellis P, Mirzanejad Y, Martinka G, Keenan S, Wood G, Arabi Y, Feinstein D, Kumar A, Dodek P, Kravetsky L, Doucette S; Cooperative Antimicrobial…
Prevalence of significant neoplasia in FOBT-positive patients on warfarin compared with those not on warfarin.Iles-Shih L, Collins JF, Holub JL, Lieberman DA. Am J Gastroenterol. 2010 Sep;105(9):2030-4; OBJECTIVES: The fecal occult blood test (FOBT) is widely used for colorectal cancer screening. However, the impact of warfarin use on FOBT sensitivity and specificity remains unclear. This…
Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism.Novacek G, Weltermann A, Sobala A, Tilg H, Petritsch W, Reinisch W, Mayer A, Haas T, Kaser A, Feichtenschlager T, Fuchssteiner H, Knoflach P, Vogelsang H, Miehsler W, Platzer R, Tillinger W, Jaritz B, Schmid A, Blaha B, Dejaco C, Eichinger S. Gastroenterology. 2010…