Colonscopia riduce mortalità di CCR un ampio studio di coorte

 Long-Term Colorectal-Cancer Incidence and Mortality after Lower Endoscopy Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A. Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C. Willett, Bernard A. Rosner, Charles S. Fuchs, Edward Giovannucci, Shuji Ogino, and Andrew T. Chan.N Engl J Med 2013; 369:1095-1105   Colonoscopy and…

PPI e rischio di recidiva di C.difficile

 Proton Pump Inhibitors and Risk for Recurrent Clostridium difficile Infection Among Inpatients.Freedberg DE, Salmasian H, Friedman C, Abrams JA. Am J Gastroenterol. 2013 Sep 24. doi: 10.1038/ajg.2013.333. [Epub ahead of print] OBJECTIVES:Observational studies suggest that proton pump inhibitors (PPIs) are a risk factor for incident Clostridium difficile infection (CDI). Data also suggest an association between PPIs…

Score per valutare comorbidità in cirrosi

 Development and Validation of a Comorbidity Scoring System for Patients with Cirrhosis.Jepsen P, Vilstrup H, Lash TL. Gastroenterology. 2013 Sep 17. [Epub ahead of print]  At least 40% of patients with cirrhosis have comorbidities, which increase mortality. We developed a cirrhosis-specific comorbidity scoring system (CirCom) to help determine how these comorbidities affect mortality, and compared…

TACE + Sorafenib se l’HCC non è resecabile : una review sistematica

     Combination Trans Arterial Chemoembolization (TACE) Plus Sorafenib for the Management of Unresectable Hepatocellular Carcinoma: A Systematic Review of the Literature.  Abdel-Rahman O, Elsayed ZA. Dig Dis Sci. 2013 Sep 18. [Epub ahead of print] Hepatocellular carcinoma (HCC) is the most common liver neoplasm and the fifth most common cancer worldwide. Intermediate stage HCC [traditionally defined…