GESTIONE NON-CHIRURGICA DELLA DIVERTICOLITE COMPLICATA CON ASCESSO: UNA REVISIONE SISTEMATICA

Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: a systematic review Hayley Fowler et al. Abstract Background: The aim of this study was to assess failure rates following nonoperative management of acute diverticulitis complicated by abscess and trends thereof. Method: Pubmed, MEDLINE, EMBASE, CINAHL, Cochrane Library, and Web of Science were systematically searched.…

CAMBIO SIMILARI NELLE IBD: INTERCAMBIABILITA’ NON EQUIVALE AD INTECAMBIABILE

The Automatic Substitution of Biosimilars: Definitions of Interchangeability are not Interchangeable Anita Afzali et al. Abstract In the USA, an interchangeability designation provides biosimilar sponsors with a pathway for achieving what is standard for small-molecule generics: pharmacy-level auto-substitution for an innovator. No other major health authority links interchangeability to automatic substitution, as all require the…