NUOVI “TARGET” PER LA COLESTASI E LA STEATOSI. UNA GRANDE REVISIONE DA “GUT” (FREE!)
Novel therapeutic targets for cholestatic and fatty liver disease Michael Trauner , Claudia Daniela Fuchs Abstract Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key pathophysiological mechanisms which can be targeted by novel therapeutic concepts that are currently developed for both areas. Nuclear receptors (NRs) are ligand-activated transcriptional regulators of key metabolic processes including hepatic…