AGGIUNGI TERAPIA ANTICOAGULANTE AL PAZIENTE CON COVID 19 PER PREVENIRE LA MORTALITA’. STUDIO OSSERVAZ. USA SU 4300 PAZIENTI

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study Christopher T Rentsch et al. Abstract Objective To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among patients admitted to hospital with…

TERLIPRESSINA FA REGREDIRE LA SINDROME EPATORENALE DI TIPO 1 NEL 40% DEI CASI

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome Florence Wong, et al. Abstract BACKGROUND The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome (HRS-1) in many parts of the world and is part of the clinical practice guidelines in Europe. METHODS We conducted a phase 3 trial to confirm the efficacy…

COLON IRRITABILE. UNA REVIEW DA CAMILLERI

Diagnosis and Treatment of Irritable Bowel Syndrome. A Review Michael Camilleri, MD Abstract Importance  The prevalence of irritable bowel syndrome (IBS) in the United States is between 7% and 16%, most common in women and young people, with annual direct costs estimated at more than $1 billion dollars in the United States. Traditionally, the diagnosis of…

UNO SCORE DI FACILE USO PER IDENTIFICARE IL PAZIENTE CON CIRROSI NEL TUO STUDIO

Can routine blood tests be modelled to detect advanced liver disease in the community: model derivation and validation using UK primary and secondary care data  Theresa Hydes et al. Abstract Objectives Most patients are unaware they have liver cirrhosis until they present with a decompensating event. We therefore aimed to develop and validate an algorithm to…

UN CALCOLATORE MOLTO ACCURATO PER LA PROGNOSI DEL PAZIENTE CON COVID-19

Development of Severe COVID-19 Adaptive Risk Predictor (SCARP), a Calculator to Predict Severe Disease or Death in Hospitalized Patients With COVID-19 FREE Shannon Wongvibulsin et al. Abstract Background: Predicting the clinical trajectory of individual patients hospitalized with coronavirus disease 2019 (COVID-19) is challenging but necessary to inform clinical care. The majority of COVID-19 prognostic tools…

Più di 140,000 differenti virus vivono nell’intestino umano.

Massive expansion of human gut bacteriophage diversity Luis F. Camarillo-Guerrer et al. Highlights • Database containing 142,809 non-redundant gut phage genomes from 28,060 metagenomes • Host assignment reveals phage diversity and host range across gut bacteria isolates • Epidemiology analysis unveils 280 viral clusters that are globally distributed • The Gubaphage is a clade that…