I TEST DI DIAGNOSI PER LA FIBROSI NELLA NAFLD: UNA META-ANALISI PER DATI INDIVIDUALI PER RIDURRE LE BIOPSIE

Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis Ferenc Emil Mózes et al. ABSTRACT Objective Liver biopsy is still needed for fibrosis staging in many patients with non-alcoholic fatty liver disease. The aims of this study were to evaluate the individual diagnostic performance of liver stiffness measurement…

GLI INIBITORI DELLA POMPA PROTONICA “PROTEGGONO” DAL DIABETE ? UNA IPOTESI ED UNA META-ANALISI INTERESSANTE

Effects of Proton Pump Inhibitors on Glycemic Control and Incident Diabetes: A Systematic Review and Meta-Analysis Carol Chiung-Hui Peng  et al. Abstract Context Whether proton pump inhibitors (PPI) can improve glycemic control among individuals with diabetes or decrease the risk of incident diabetes in the general population is unclear. Objective To evaluate the impact of…

MODULAZIONE DEL MICROBIOTA E PREVENZIONE DEL CANCRO DEL PANCREAS: UNA MAGNIFICA REVISIONE, GRANDI PROMESSE

Therapeutic potential of microbial modulation in pancreatic cancer   Vidhi Chandra, Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is an aggressive disease with a poor prognosis.1 Surgery is the only potential curative treatment, but it is only possible in patients with early-stage disease, and most patients present with non-resectable disease.1 Even in patients who…

SEI UN “BAYESIANO” OD UN “FREQUENTISTA” ? VERIFICA IL TUO ALLINEAMENTO DA “TOWARDS DATA SCIENCE” !

Statistics: Are you Bayesian or Frequentist? The fastest way to diagnose your statistical alignment Cassie Kozyrkov What if I told you that I can show you the difference between Bayesian and Frequentist statistics with one single coin toss? Before we go any further, the demonstration works best in video form, so don’t read the summary and…

SARA’ LA GRAN BRETAGNA IL PRIMO PAESE AD ARRENDERSI AL COVID? UN’AMARA RIFLESSIONE SU “MEDIUM”

How Britain Became the First Country in the World to Surrender to Covid This is What it Means to Be the Dumbest Country in the World Umair Haque You might have long thought America — or your country — was the dumbest in the world. Ah, my friend. Here’s a situation so surreal that it’s…

“LIKELIHOOD RATIO” PER INTERPRETARE MEGLIO I TRIAL CLINICI: NON LO SAPEVATE ?!

How to use likelihood ratios to interpret evidence from randomized trials Thomas V.Perneger Highlights • The likelihood ratio represents evidence from a study about the relative merits of two hypotheses – typically, in a clinical trial, the hypotheses that the new treatment is effective (at a specific level), vs. that it is not. • The likelihood…