DIECI ANNI SENZA ALESSANDRO LIBERATI. “I LIBERATI’s PRINCIPLES”: IL RICORDO DI ANTONIO ADDIS E LUCA DE FIORE (FREE)

I Liberati’s principles dieci anni dopo ANTONIO ADDIS, LUCA DE FIORE Riassunto. A dieci anni dalla morte di Alessandro Liberati gli autori si chiedono se e quanto siano ancora importanti i principii che hanno guidato l’azione del medico e ricercatore, fondatore del centro italiano della Cochrane Collaboration. La stella polare del pensiero di Liberati può…

ENCEFALOPATIA EPATICA:OLTRE L’AMMONIO. UNA RAPIDA REVISIONE 2022 DALLA SOCIETA’ AMERICANA PER LO STUDIO DEL FEGATO (AASLD)(FREE)

Hepatic encephalopathy: Thinking Beyond ammonia Hanna Blaney, M.D., M.P.H.,* and Sharon DeMorrow, Ph.D Hepatic encephalopathy (HE) is a syndrome of impaired brain function due to acute and chronic liver disease and/ or portosystemic shunting. Manifestations range from subclinical psychiatric and neurological disturbances to coma. It is associated with high morbidity and mortality and contributes to…

VERSO NUOVE EVIDENZE PER I PROBIOTICI 2: EFFETTO NELLE FASI PRECOCI DI INFEZIONE DA COVID-19 ? UNA REVIEW (FREE)

Gut Dysbiosis during COVID-19 and Potential Effect of Probiotics Yuan-Pin Hung et al. Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus of the family Coronaviridae, causes coronavirus disease 2019 (COVID-19), an influenza-like disease that chiefly infects the lungs through respiratory transmission. The spike protein of SARS-CoV-2, a transmembrane protein in its outer…

VERSO NUOVE EVIDENZE PER I PROBIOTICI: L’USO PERIOPERATORIO NEI PAZIENTI SOTTOPOSTI A PANCREATICODUODENECTOMIA. UNA META-ANALISI (FREE)

Effects of Perioperative Probiotics and Synbiotics on Pancreaticoduodenectomy Patients: A Meta-Analysis of Randomized Controlled Trials Gang Tang et al. Post-pancreaticoduodenectomy infections cause mortality, morbidity, and prolonged antibiotic use. Probiotics or synbiotics may be advantageous for preventing postoperative infections, but their benefits on pancreaticoduodenectomy outcomes are controversial. This study evaluated the efficacy of probiotics and synbiotics…

COLONSCOPIA E TERAPIA DOPO DIVERTICOLITE: UNA LINEA GUIDA DALL’AMERICAN COLLEGE OF PHYSICIANS PER PREVENIRE LA RECIDIVA SUGLI ANNALS (FREE)

Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians Amir Qaseem et al. Abstract Description: The American College of Physicians (ACP) developed this guideline to provide clinical recommendations on the role of colonoscopy for diagnostic evaluation of colorectal cancer (CRC) after…

I DUE NUOVI ANTIVIRALI ORALI PER IL COVID-19. UNA SCHEDA RIASSUNTIVA DA MPR

Oral Antiviral Treatments for COVID-19: Molnupiravir and Paxlovid Diana Ernst, RPh Molnupiravir Paxlovid Company Merck Pfizer Generic Name and Formulation Molnupiravir 200mg; capsules. Nirmatrelvir 150mg; ritonavir 100mg; tablets. Pharmacological Class Nucleoside analogue that inhibits SARS-CoV-2 replication by viral mutagenesis. SARS-CoV-2 main protease inhibitor + HIV-1 protease inhibitor and CYP3A inhibitor. Indication For the treatment of…