CONFRONTO SULLA PERFORMANCE DI SCORE PER EMORRAGIA DIGESTIVA INFERIORE. UNA META-ANALISI (FREE) DA JAMA.

Comparison of Risk Scores for Lower Gastrointestinal Bleeding. A Systematic Review and Meta-analysis Majed Almaghrab et al. Key Points Question  Which risk score for lower gastrointestinal bleeding best discriminates safe discharge, major bleeding, need for transfusion, and need for hemostasis? Findings  In this systematic review and meta-analysis of 9 studies of 4 risk scores, the Oakland score was…

RISORSE UMANE PER LA SALUTE. UNA ATTENTA ANALISI SU 204 PAESI 1990-2019. DA “LANCET” (FREE). Funding Bill & Melinda Gates Foundation.

Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 GBD 2019 Human Resources for Health Collaborators Summary Background Human resources for health (HRH) include a range of occupations that…

EBM E CURA. LA EBM NON E’ UN NUOVO PARADIGMA. UNA GRANDE RIFLESSIONE DI MARINA DAVOLI E LUCA DE FIORE. “FREE” DA “IL PUNTO”.

Non sarà un’avventura Basare sulle prove la cura e le politiche sanitarie è la sola strada possibile. Di Marina Davoli e Luca De Fiore 4 giugno 2022  367  0  leggi dopo 13 minuti di lettura Nel 2014 tre stimati ricercatori del Regno Unito – Trisha Greenhalgh, Jeremy Howick e Neal Maskrey – spiegavano perché la medicina basata sulle prove attraversava…

LA NASCITA DEL “P-VALUE”. UNA STORIA INTERESSANTE CON RISVOLTI RAZZISTI ! DA Towards Data Science. FREE!

p-values: A Legacy of “Scientific Racism” A deeper look at the untold history of p-values and its legacy Raveena Jay Disclaimer: I’ll be putting quotes around certain words, like race, racial measurements”, etc. because not only are these terms loaded with historical discrimination, but “race” is un-scientific. A “race” of people is an un-scientific term. Also, the…

BREAKING NEWS ! REGRESSIONE TOTALE DEL CANCRO DEL RETTO LOCALMENTE AVANZATO CON BLOCCO DELLA PROGRAMMED DEATH (PD-1 ). “FREE” DAL NEJM

PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer Andrea Cercek et al. Abstract BACKGROUND Neoadjuvant chemotherapy and radiation followed by surgical resection of the rectum is a standard treatment for locally advanced rectal cancer. A subset of rectal cancer is caused by a deficiency in mismatch repair. Because mismatch repair–deficient colorectal cancer is responsive…

IL MICROBIOTA E’ ASSOCIATO ALLA RISCHIO DI ICTUS ED ALLA SUA SEVERITA’! UNA OTTIMA SINTESI DA Medscape Gastroenterology DOPO IL CONGRESSO DELLA ESOC (European Stroke Organisation Conference).

Gut Bacteria Linked to Stroke Severity, Risk Kelli Whitlock Burton Two new studies identifying strains of gut microbiota associated with more severe strokes and worse post-stroke recovery point to a possible role for the gut microbiome in preventing stroke and improving outcomes. Researchers identified gut microbiota that were different in stroke patients compared to control…