RILETTURA ! E COME FARE A VALUTARE LA PROBABILITA’ PRE-TEST PRIMA DI VALUTARE UN ESAME DI LABORATORIO O DI IMAGING ? DAL “J.OF CLINICAL EPIDEMIOLOGY, 2021” (FREE)

Key concepts in clinical epidemiology: Estimating pre-test probability Elenore Judy B. Uy Abstract Appropriate medical management largely hinges on correctly diagnosing the underlying disease. Often, clinicians are faced with a dizzying array of accurate, albeit expensive and/or invasive diagnostic tests. What tends to be overlooked is that the probability of a disease once the test…

OCCHIO ALLA REAL-WORLD EVIDENCE! METODI, SFIDE ED OPPORTUNITA’. DAL”BMC Med Res Methodol ” (FREE)

Real-world data: a brief review of the methods, applications, challenges and opportunities Fang Liu, Panagiotakos Demosthenes Abstract Background: The increased adoption of the internet, social media, wearable devices, e-health services, and other technology-driven services in medicine and healthcare has led to the rapid generation of various types of digital data, providing a valuable data source beyond the…

I NUOVI AGENTI PER LA MALATTIA COLESTATICA . UNA OTTIMA REVIEW DA “J. OF HEPATOLOGY” (FREE)

Primary biliary cholangitis as a roadmap for the development of novel treatments of cholestatic liver diseases Frederik Nevens et al. summary The discovery of nuclear receptors and transporters has contribute to the development of new drugs for the treatment of cholestatic liver diseases. Especially progress has been made in the second line therapy of PBC.…

UNA RILETTURA ! LA RICERCA DELLA LETTERATURA: I DATA BASE DISPONIBILI SONO PIU’ DI QUELLO CHE PENSATE! DA”STUDENTS 4 BEST EVIDENCE” (FREE).

Literature searches: what databases are available? Posted on 6th April 2021 by Izabel de Oliveira Many types of research require a search of the medical literature as part of the process of understanding the current evidence or knowledge base. This can be done using one or more biomedical bibliographic databases. [1] Bibliographic databases make the information…

ENCEFALOPATIA EPATICA IN OUTPATIENTS. IL RUOLO DELLA ALBUMINA IN UN RCT IMPORTANTE. LO STUDIO “HEAL”. DAL “J. OF HEPATOLOGY”

A double-blind randomized placebo-controlled trial of albumin in outpatients with hepatic encephalopathy: HEAL study Andrew Fagan et al. Highlights • Persistent cognitive impairment affects quality of life in individuals with cirrhosis who have had prior episodes of HE. • We found in a randomized-controlled trial that weekly albumin infusions improved cognition vs. placebo. • Albumin improved quality…