Advances in the gut microbiome and mood disorders Mörkl, Sabrina et al. Abstract Purpose of review The gut microbiome is in constant bidirectional communication with the brain through the microbiota-gut-brain-axis. Mood disorders are among the most common psychiatric disorders and include major depressive disorder and bipolar disorder. The gut microbiome is altered in individuals with…
In conversation with John Cryan Paraminder Dhillon and John F. Cryan Abstract John F. Cryan is Chair of the Department of Anatomy and Neuroscience, Principal Investigator in the APC Microbiome Ireland Institute and Vice President for Research and Innovation at University College of Cork, Ireland. He obtained his bachelor’s and doctoral degrees (in Biochemistry and…
Histologic Subtyping of Gastric Intestinal Metaplasia: Overview and Considerations for Clinical Practice Shailja C. Shah et al Gastric cancer remains the third leading cause of cancer-related mortality and the fifth most common cancer worldwide, responsible for an estimated 1 million new cases and more than 780,000 deaths in 2018 alone.1 Gastric adenocarcinoma is the most…
Inclusion of nonrandomized studies of interventions in systematic reviews of interventions: updated guidance from the Agency for Health Care Research and Quality Effective Health Care program Ian J. Saldanha et al. Abstract Objectives We developed guidance to inform decisions regarding the inclusion of nonrandomized studies of interventions (NRSIs) in systematic reviews (SRs) of the effects…
The person-to-person transmission landscape of the gut and oral microbiomes Mireia Valles-Colome et al. Abstract The human microbiome is an integral component of the human body and a co-determinant of several health conditions1,2. However, the extent to which interpersonal relations shape the individual genetic makeup of the microbiome and its transmission within and across populations…
Aifa tra scienza e politica Riordino, rivoluzione, restaurazione. Cosa sta succedendo lo racconta Luca De Fiore Cosa sta succedendo. L’8 novembre 2022 un decreto legge ha ridisegnato l’Agenzia italiana del farmaco [1]: la figura del direttore generale è giudicata non più necessaria nonostante detenga tutti i poteri di gestione di Aifa e ne diriga l’attività, emanando…