Acute Kidney Injury in Patients with Cirrhosis Mitra K. Nadim, M.D., and Guadalupe Garcia-Tsao Acute kidney injury (AKI) is a common condition in patients with cirrhosis. It occurs in up to 50% of hospitalized patients with cirrhosis and in 58% of such patients in the intensive care unit (ICU).1-5 AKI is associated with high morbidity and mortality…
Management of Hepatocellular Carcinoma. A Review Zachary J. Brown et al. Abstract Importance Hepatocellular carcinoma (HCC) is the sixth most common malignancy and fourth leading cause of cancer-related death worldwide. Recent advances in systemic and locoregional therapies have led to changes in many guidelines regarding systemic therapy, as well as the possibility to downstage patients to undergo…
Micronutrient Supplementation to Reduce Cardiovascular Risk Peng An et al. ABSTRACT BACKGROUND Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified. OBJECTIVES The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifies the impact of micronutrients…
Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) Melanie J. Davies et al. The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the previous consensus statements on…
When dignity meets evidence Seye Abimbola Throughout its 40-year history, proponents of evidence-based practice, including people also advocating for dignity-based practice, have pointed at its blind spots. The need for dignity-based practice is now recognised in health care (eg, with shared decision making in caregiving and patient-determined outcome measures in research) and in health policy…
The role of diet in shaping human gut microbiota Emanuele Rinninella et al. Abstract Gut microbiota plays a fundamental role within human health, and exerts key functions within the human body. Diet is one of the most powerful modulators of gut microbiota functions and composition. This complex interplay involves also the immune system and the intestinal…