I PROBIOTICI MIGLIORANO COLESTEROLO E TRIGLICERIDI NELLA STEATOSI EPATICA. UNA “UMBRELLA” META-ANALISI ! DA “Systematic Reviews” (FREE)

Efects of gut microbial therapy on lipid profile in individuals with non-alcoholic fatty liver disease: an umbrella meta-analysis study Amirhossein Naghipour et al. Background Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, is closely associated with metabolic conditions such as obesity and diabetes mellitus, which significantly impact human health outcomes. The impaired lipid…

APPENDICITE ACUTA! LA NUOVA TECNICA PER VIA ENDOSCOPICA HA LE STESSE PROBABILITA’ DI SUCCESSO DELLA APPENDICECTOMIA! UNA OTTIMA META-ANALISI DA UN GRUPPO ITALIANO. DA” SURGERY” (FREE).

Endoscopic retrograde appendicitis therapy versus appendectomy or antibiotics in the modern approach to uncomplicated acute appendicitis: A systematic review and meta-analysis Francesco Pata et al. Abstract Introduction: Endoscopic retrograde appendicitis therapy has been proposed as an alternative strategy for treating appendicitis, but debate exists on its role compared with conventional treatment. Methods: This systematic review was performed…

ATTENZIONE: GLI INIBITORI DELLA POMPA PROTONICA POTREBBERO ELEVARE IL RISCHIO CARDIOVASCOLARE E LA MORTALITA’ NEI PAZIENTI DIABETICI. DA”J Clin Endocrinol Metab “

Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes Tingting Geng et al. Abstract Context: Proton pump inhibitors (PPIs) are widely used drugs for gastric acid-related diseases and may affect the gut microbiome. Objective: We aimed to evaluate the associations of PPI use with risks of cardiovascular disease (CVD)…

INIBITORI DELLA POMPA PROTONICA: ATTENZIONE, POTREBBERO AUMENTARE IL RISCHIO DI DEMENZA NEL LONG TERM. DA “Alzheimer’s & Dementia” (FREE).

Proton pump inhibitors and dementia: A nationwide population-based study Nelsan Pourhad et al. Abstract INTRODUCTION Proton pump inhibitors (PPIs) may increase dementia risk. However, it is currently unknown whether timing of exposure or age at dementia diagnosis influence the risk. METHODS We assessed associations between cumulative PPI use and dementia at different ages in a…

N-of-1 TRIALS. A VOLTE RITORNANO! LA GRANDE IMPORTANZA DELLA ANALISI DELLA RISPOSTA SUGLI STESSI PAZIENTI! DA “Journal of Clinical and Translational Science 2023” (FREE).

The use of N-of-1 trials to generate real-world evidence for optimal treatment of individuals and populations Harry P. Selker et al. Abstract Introduction:Ideally, real-world data (RWD) collected to generate real-world evidence (RWE) should lead to impact on the care and health of real-world patients. Deriving from care in which clinicians and patients try various treatments…

NAFLD: DIAGNOSI E GESTIONE CLINICA DA UNA OTTIMA LINEA GUIDA SUL”NEJM” (OTTOBRE 2023).

Diagnosis and Management of Nonalcoholic Fatty Liver Disease Peggy B. Leung, MD; Andrew M. Davis, MD, MPH; Sonal Kumar, MD, MPH GUIDELINE TITLE American Association of Clinical Endocrinology (AACE) Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings RELEASE DATE May 2022 DEVELOPER AND…