COLITE ULCEROSA SEVERA: DOPO GLI STEROIDI E’ MEGLIO INFLIXIMAB + AZATIOPRINA O LA SOLA AZATIOPRINA? ATTENZIONE AL TRIAL “ACTIVE” ! DA “GUT”

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Top-down infliximab plus azathioprine versus azathioprine alone in patients with acute severe ulcerative colitis responsive to intravenous steroids: a parallel, open-label randomised controlled trial, the ACTIVE trial Aurelien Amiot et al.  Abstract Background It is unknown which maintenance therapy is the most effective option for patients admitted for an acute severe ulcerative colitis (ASUC) episode responding…

UN’OTTIMA REVIEW SULLA PRIMARY BILIARY CHOLANGITIS. ANDATE A VEDERE ANCHE IL RUOLO DELL’ACIDO OBETICOLICO, OGGI IN DISCUSSIONE. DA “THE LANCET” (FREE)

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Primary biliary cholangitis Prof Atsushi Tanaka et al. Summary Primary biliary cholangitis is a chronic, autoimmune, cholestatic disease that mainly affects women aged 40–70 years. Recent epidemiological studies have shown an increasing incidence worldwide despite geographical heterogeneity and a decrease in the female-to-male ratio of those the disease affects. Similar to other autoimmune diseases, primary…

OSTRUZIONE BILIARE DISTALE DA NEOPLASIA: COLEDOCODUODENOSTOMIA VIA ECOENDO O ERCP ? L’ACCESSO PERCUTANEO DOVREBBE ESSERE ABBANDONATO. UNA OTTIMA NETWORK META-ANALISI ITALIANA. DA “DIGESTIVE & LIVER DISEASE “

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Primary drainage of distal malignant biliary obstruction: A comparative network meta-analysis Gaetano Lauri et al. Abstract Background The effectiveness of various primary upfront drainage techniques for distal malignant biliary obstructions (dMBO) is not well-established. Objective To compare the technical and clinical success rates and adverse event (AE) rates of various primary drainage techniques. Methods We…