SEMAGLUTIDE MIGLIORA LA ISTOLOGIA NELLA MASH (METABOLIC ASSOCIATED STEATOHEPATITIS). IL TRIAL VS PLACEBO “ESSENCE”. RISULTATI PRELIMINARI SU 800 PAZIENTI A 2 ANNI. DA “NEJM” (NON FREE PURTROPPO)

ECOGRAFIA ED ECOENDOSCOPIA, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, NEWSLETTER, NUTRIZIONE

Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis  Arun J. Sanyal et al. for the ESSENCE Study Group Abstract Background Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Methods In this ongoing phase 3, multicenter, randomized, double-blind, placebo-controlled trial, we assigned 1197 patients with biopsy-defined…

CANCRO DEL RETTO. L’APPROCCIO CON ROBOT VS LAPAROSCOPIA. LO STUDIO “REAL” SU 1240 PAZIENTI. ATTENZIONE: LA CHIRURGIA ROBOTICA E’ SUPERIORE! DA”JAMA” (FREE!)

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Robotic vs Laparoscopic Surgery for Middle and Low Rectal Cancer: The REAL Randomized Clinical Trial Qingyang Feng, MD et al. Key Points Question  Can the use of robotic surgery reduce the locoregional recurrence rate of middle and low rectal cancer compared with the use of laparoscopic surgery? Findings  In this randomized clinical trial including patients with middle…

BUONA NOTTE. LE REVISIONI SISTEMATICHE SONO INQUINATE DALLE RIVISTE PIRATA! LEGGETE PER FAVORE ! DA “JAMA NETWORK OPEN” (FREE!)

AI, INTELLIGENZA ARTIFICIALE, GASTROENTEROLOGIA, METODOLOGIA, NEWSLETTER

Citation Contamination by Paper Mill Articles in Systematic Reviews of the Life Sciences Gengyan Tang, MA1; Hao Cai, MS2 Key Points Question  Do paper mill articles contaminate systematic reviews in the life sciences, and what are their implications for the integrity of evidence synthesis? Findings  In a cross-sectional study of 200 000 systematic reviews published between 2013 and 2024, 0.15% incorporated retracted paper…

TUMORI NEUROENDOCRINI: POSITION STATEMENT della European Neuroendocrine Tumor Society (ENETS) SULLA GESTIONE ENDOSCOPICA ! Dal Francesco Panzuto e coll. su “J. OF NEUROENDOCRINOLOGY” (FREE!)

CHIRURGIA, ENDOSCOPIA, GASTROENTEROLOGIA, NEWSLETTER

Controversies in NEN: An ENETS position statement on the endoscopic management of localised gastric, duodenal and rectal neuroendocrine neoplasms Francesco Panzuto et al. Abstract Gastric, duodenal and rectal neuroendocrine tumours (NETs) are increasingly detected due to advances in endoscopic imaging. While international guidelines provide criteria for endoscopic management, several aspects remain controversial due to limited…