JAK INIBITORI VS ANTI-TNF NELLE MALATTIE INFIAMMATORIE IMMUNOMEDIATE. CHI VINCE IN SICUREZZA? UNA REVISIONE SISTEMATICA CON META-ANALISI. DA” JAMA Netw Open” (FREE)

Comparative Safety of JAK Inhibitors vs TNF Antagonists in Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis Virginia Solitano et al. Abstract Importance: Janus kinase (JAK) inhibitors are highly effective medications for several immune-mediated inflammatory diseases (IMIDs). However, safety concerns have led to regulatory restrictions. Objective: To compare the risk of adverse events with JAK inhibitors vs…

PREVENZIONE DELLA PANCREATITE POST-ERCP. CRIOPREVENZIONE LOCALE? UN TRIAL MOLTO INTERESSANTE DAL GIAPPONE. DA “AMERICAN JOURNAL OF GASTROENTEROLOGY”

Local Postprocedural Cryoprevention Significantly Reduces the Incidence of Post-ERCP Pancreatitis: A Multicenter Randomized Controlled Trial Azuma, Shunjiro MD et al. INTRODUCTION: Postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is a common, potentially serious adverse event of ERCP. Although rectal nonsteroidal anti-inflammatory drugs are recommended for prevention, their use in Japan is limited due to dosage concerns.…

GASTROPARESI: LE LINEE GUIDA AGA EVIDENCE -BASED OTTOBRE 2025. DA “GASTROENTEROLOGY” (FREE)

AGA Clinical Practice Guideline on Management of Gastroparesis Kyle Staller et al. Abstract Background & Aims Gastroparesis is a complex gastric motility disorder characterized by nausea, vomiting, and other symptoms associated with a delay in gastric emptying in the absence of mechanical obstruction. Variations in diagnostic testing and limited effective treatments make caring for this patient…