MALATTIE EPATICHE ASSOCIATE AD ALCOL: UN RUOLO PER GLI AGONISTI DEI RECETTORI GLP-1 ! DA” THE LANCET gastroenterology & hepatology””

GLP-1 receptor agonists in alcohol use disorder and alcohol-associated liver disease Ashwani K Singal, Lorenzo Leggio GLP-1 is a hormone produced by intestinal L-type enteroendocrine cells, endocrine pancreas, and nucleus tractus solitarius neurons in the brain. GLP-1 acts via the GLP-1 receptor and provides beneficial effects on food intake, energy homoeostasis, glucose metabolism, hepatic function,…

COLANGITE BILIARE PRIMITIVA (CBP). E’ TEMPO DI RIPENSARE AL RUOLO DEL BEZAFIBRATO! UN’OTTIMO EDITORIALE DA “Nat Rev Gastroenterol Hepatol” purtroppo non-free

Bezafibrate for primary biliary cholangitis: time to act on the evidence Christophe Corpechot et al. After the regulatory rejection of obeticholic acid, peroxisome proliferator-activated receptor (PPAR) agonists have emerged as the leading second-line candidates for primary biliary cholangitis, pending defnitive approval. Of these, only bezafbrate — a low-cost, widely available generic — has demonstrated long-term…