Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder, with a prevalence of 4% to 10%. It is a chronic condition characterized by abdominal pain in conjunction with altered bowel habits, abdominal distention, or bloating. IBS can present with 3 different defecation patterns: IBS with constipation, IBS with diarrhea, or mixed IBS. Recent advances in IBS include a positive diagnosis based on symptom-based criteria and a treatment plan based on IBS subtype and bothersome symptoms. In addition to diet and lifestyle modifications, this article discusses the role of new pharmacologic and nonpharmacologic treatment options for the management of IBS.
Treatment… General measures, such as establishing an effective patient–clinician relationship, educating patients about IBS, and implementing lifestyle changes (including dietary advice, physical activity, and stress management), are essential to effective IBS management. If lifestyle changes do not completely relieve IBS symptoms, several medications may be helpful. Pharmacologic therapy should target the individual patient’s symptom pattern, and options include antispasmodics, laxatives, antidiarrheal agents, manipulation of microflora, and several FDAapproved IBS-specific drugs. Central neuromodulators are an essential treatment in managing IBS when symptoms, particularly pain, are dominant or when there are psychological comorbidities. CLINICAL BOTTOM LINE
LEGGI TUTTO https://pubmed.ncbi.nlm.nih.gov/40789179/#:~:text=DOI%3A-,10.7326/ANNALS%2D25%2D01965,-Abstract
