NEOPLASIE PANCREAS RESECABILI: PANCREATODUODENECTOMIA MINIMAMENTE INVASIVA VS OPEN. SAFETY FIRST ! UN GRANDE COMMENTO EDITORIALE DA “NEJM EVIDENCE” (FREE)

Minimally Invasive Pancreatoduodenectomy — Safety First Authors: Rachel H. Joung, M.D., M.S., and Rebecca A. Snyder, M.D., M.P.H. Recent advances in surgical technology have led to increased adoption of minimally invasive pancreatectomy despite limited prospective evidence regarding the safety and efficacy of this approach. Although minimally invasive techniques may offer the potential for earlier recovery, few studies to date have directly…

NEOPLASIE PANCREAS RESECABILI: LA PANCREATODUODENECTOMIA MINIMAMENTE INVASIVA EQUIVALE ALLA OPEN. UN GRANDE TRIAL MULTICENTRICO DA 14 CENTRI SU 288 PAZIENTI. DA “NEJM EVIDENCE” (FREE)

Minimally Invasive versus Open Pancreatoduodenectomy for Resectable Neoplasms  Nine de Graaf, et al. Abstract Background Minimally invasive pancreatoduodenectomy (MIPD) might accelerate postoperative recovery in patients with primary resectable neoplasm compared with open pancreatoduodenectomy (OPD), although the safety of MIPD remains debated. We aimed to assess whether MIPD is noninferior to OPD for overall complications and…

CIRROSI SCOMPENSATA : NIENTE DA FARE. SIMVASTATINA + RIFAXIMINA NON MIGLIORANO GLI ESITI. UN TRIAL MULTICENTRICO DA 14 CENTRI EUROPEI SU 237 PAZIENTI. DA “JAMA” (FREE!)

Simvastatin and Rifaximin in Decompensated Cirrhosis. A Randomized Clinical Trial Elisa Pose et al. Key Points Question  Is the combination of simvastatin and rifaximin useful to prevent severe complications of liver cirrhosis? Findings  In this randomized clinical trial that included 237 patients with decompensated cirrhosis, no significant differences were found in terms of the incidence of severe…