Efects of gut microbial therapy on lipid profile in individuals with non-alcoholic fatty liver disease: an umbrella meta-analysis study Amirhossein…
Endoscopic retrograde appendicitis therapy versus appendectomy or antibiotics in the modern approach to uncomplicated acute appendicitis: A systematic review and…
Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes Tingting Geng et…
Proton pump inhibitors and dementia: A nationwide population-based study Nelsan Pourhad et al. Abstract INTRODUCTION Proton pump inhibitors (PPIs) may…
The use of N-of-1 trials to generate real-world evidence for optimal treatment of individuals and populations Harry P. Selker et…
Diagnosis and Management of Nonalcoholic Fatty Liver Disease Peggy B. Leung, MD; Andrew M. Davis, MD, MPH; Sonal Kumar, MD,…
Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Bas L. A. M. Weusten et al.…
Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma. A Systematic Review and Meta-Analysis Enrui Xie et al. IMPORTANCE…
Thalidomide for Recurrent Bleeding Due to Small-Intestinal Angiodysplasia Huimin Chen et al. Abstract BACKGROUND Recurrent bleeding from the small intestine…
AGA Clinical Practice Update on the Role of Noninvasive Biomarkers in the Evaluation and Management of Nonalcoholic Fatty Liver Disease:…
Updates to the modern diagnosis of GERD: Lyon consensus 2.0 Prakash Gyawal et al. Abstract The Lyon Consensus provides…
Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and Antiviral Drugs, a Narrative Review Angelo Del Gaudio et al Abstract…
Replication games: how to make reproducibility research more systematic Abel Brodeur, Anna Dreber, Fernando Hoces de la Guardia & Edward Miguel…
Hepatitis C Marianne Martinello, PhD et al. Summary Hepatitis C virus (HCV) is a hepatotropic RNA virus that can cause…
Ulcerative Colitis in Adults A Review Beatriz Gros, MD; Gilaad G. Kaplan, MD, MPH This review focuses on the epidemiology,…
Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions:…
Early Ileocecal Resection for Crohn’s Disease Is Associated With Improved Long-term Outcomes Compared With Anti-Tumor Necrosis Factor Therapy: A Population-Based…
The pursuit of optimal semaglutide dosing in type 2 diabetes continues Christina H Sherrill , Andrew Y Hwang Diabetes remains a…
Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis Vivek C. Goodoory et al. BACKGROUND & AIMS: Some…
Defining Interactions Between the Genome, Epigenome, and the Environment in Inflammatory Bowel Disease: Progress and Prospects Alexandra J. Noble et…
Etiology, Diagnosis, and Modern Management of Chronic Pancreatitis. A Systematic Review Stephanie M. Cohen, MD; Tara S. Kent, MD Key PointsQuestion What…
Biopsy and blood-based molecular biomarker of inflammation in IBD Carmen Argmann et al ABSTRACT Objective IBD therapies and treatments are evolving…
ACG Clinical Guideline: Diagnosis and Management of Biliary Strictures Elmunzer, B. Joseph et al Abstract A biliary stricture is an abnormal narrowing…
Hepatitis D Virus Infection Tarik Asselah and Mario Rizzetto Hepatitis D virus (HDV), also known as hepatitis delta virus, is…
Hemostatic Powder vs Standard Endoscopic Treatment for Gastrointestinal Tumor Bleeding: A Multicenter Randomized Trial Rapat Pittayanon et al. Background & Aims…
The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease Loris Riccardo…
Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept Alessandro Vitale e HCC Special Interest Group of the…
Yuval Noah Harari argues that artificial intelligence has hacked the operating system of human civilization. Fears of artificial intelligence (AI)…
Meta-Analysis of Randomized Clinical Trials on Long-Term Outcomes of Surgical Treatment of Perforated Diverticulitis Horesh, Nir et al. Abstract Objective: Assess…
Emerging issues in probiotic safety: 2023 perspectives Daniel Merenstein et al. ABSTRACT Probiotics are used for both generally healthy consumers…
Peer review before trial conduct could increase research value and reduce waste Maximilian Siebert , Florian Naudet , and John P.A. Ioannidis Highlights °…
Guidance to best tools and practices for systematic reviews Kat Kolaski1, Lynne Romeiser Logan, and John P. A. Ioannidis Abstract Data continue to…
Preventing acute diverticulitis. any roles for non-absorbable antibiotics? in search of evidence: a systematic review, meta-analysis, and trial sequential analysis…
Benefits, Limits, and Risks of GPT-4 as an AI Chatbot for Medicine Peter Lee et al. The uses of artificial…
Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following DiverticulitisPrespecified 2-Year Analysis of the LASER Randomized…
Colorectal Cancer Subtyping With Microbiome—A Game Changer for Personalized Medicine? Chi Chun Wong, Jun Yu Colorectal cancer (CRC) was one…
Bile Acid Sequestrants in Microscopic Colitis: Clinical Outcomes and Utility of Bile Acid Testing June Tome et al. Abstract BACKGROUND Bile…
Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany Nayeon Ahn et al.…
Diagnosis and Management of Cirrhosis and Its Complications. A Review Elliot B. Tapper, Neehar D. Parikh, Abstract Importance Cirrhosis affects approximately 2.2…
Mortality Outcomes by Fibrosis Stage in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis Cheng Han Ng et al.…
Rifaximin-α in alcohol-associated liver disease Chencheng Xie et al Alcohol-associated liver disease is the most common cause of cirrhosis and…
Rifaximin-α for liver fibrosis in patients with alcohol-related liver disease (GALA-RIF): a randomised, double-blind, placebo-controlled, phase 2 trial Mads Israelsen…
Acute Kidney Injury in Patients with Cirrhosis Mitra K. Nadim, M.D., and Guadalupe Garcia-Tsao Acute kidney injury (AKI) is a common…
Management of Hepatocellular Carcinoma. A Review Zachary J. Brown et al. Abstract Importance Hepatocellular carcinoma (HCC) is the sixth most common malignancy…
Micronutrient Supplementation to Reduce Cardiovascular Risk Peng An et al. ABSTRACT BACKGROUND Healthy dietary patterns are rich in micronutrients, but…
Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European…
When dignity meets evidence Seye Abimbola Throughout its 40-year history, proponents of evidence-based practice, including people also advocating for dignity-based…
The role of diet in shaping human gut microbiota Emanuele Rinninella et al. Abstract Gut microbiota plays a fundamental role within…
Does Alteration of the Microbiome Cause Diverticular Disease? Jeffrey L. Roberson, MD, Lillias M. Maguire, MD Abstract The role of…
Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case–control and cohort…
Selenium and immune function: a systematic review and meta-analysis of experimental human studies TOMMASO FILIPPINI et al Abstract Background Selenium…
Clinical Outcomes of Intraductal Papillary Mucinous Neoplasms With Dilatation of the Main Pancreatic Duct. Tsuyoshi Hamada et al. BACKGROUND &…
Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis COVID-19 Forecasting Team Summary Background Understanding the level and…
Aspirin With or Without Statin in Individuals Without Atherosclerotic Cardiovascular Disease Across Risk Categories Safi U. Khan et al Abstract…
AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis Siddharth Singh et al. Background…
Use of biologics for the management of Crohn’s disease: IG-IBD clinical guidelines based on the GRADE methodology FABIO MACALUSO ED…
Randomised, Placebo-controlled Trial and Meta-analysis Show Benefit of Ondansetron for Irritable Bowel Syndrome with Diarrhoea: The TRITON Trial Gunn, David…
Systematic Review and Meta-Analysis on the Effects of Lactulose and Rifaximin on Patient-Reported Outcomes in Hepatic Encephalopathy Andrew M. Moon…
Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease: a systematic review and meta-analysis Josefin Soppert et al. Abstract…
Assessing the usefulness of randomized trials in obstetrics and gynaecology Janneke van ‘t Hooft et al. Health care professionals will…
Long-term outcomes of peroral endoscopic myotomy for achalasia: a systematic review and meta-analysis Edoardo Vespa et al. Abstract Background The long-term…
Comparison of assessment tools in acute upper gastrointestinal bleeding: Which one at which time point? Riccardo Marmo et al. Abstract…
Canada’s Guidance on Alcohol and Health: Final Report This document was published by the Canadian Centre on Substance Use and…
GUT MICROBIAL METABOLISM OF 5-ASA IS PROSPECTIVELY ASSOCIATED WITH TREATMENT FAILURE IN PATIENTS WITH IBD Raaj Mehta et al. Abstract…
Practical Guide to Designing a Clinical Trial in Surgery Panos Kougias et al A randomized clinical trial represents a controlled…
Gut Microbiota Modulation of Efficacy and Toxicity of Cancer Chemotherapy and Immunotherapy Despoina Chrysostomou et al. Accumulating evidence supports not…
American College of Gastroenterology Guidelines Update: Diagnosis and Management of Celiac Disease Rubio-Tapia, Alberto et al. Abstract This guideline presents…
Advances in the gut microbiome and mood disorders Mörkl, Sabrina et al. Abstract Purpose of review The gut microbiome is…
In conversation with John Cryan Paraminder Dhillon and John F. Cryan Abstract John F. Cryan is Chair of the Department…
Histologic Subtyping of Gastric Intestinal Metaplasia: Overview and Considerations for Clinical Practice Shailja C. Shah et al Gastric cancer remains…
Inclusion of nonrandomized studies of interventions in systematic reviews of interventions: updated guidance from the Agency for Health Care Research…
The person-to-person transmission landscape of the gut and oral microbiomes Mireia Valles-Colome et al. Abstract The human microbiome is an…
Aifa tra scienza e politica Riordino, rivoluzione, restaurazione. Cosa sta succedendo lo racconta Luca De Fiore Cosa sta succedendo. L’8 novembre…
Current understanding of the intratumoral microbiome in various tumors Chen Xue et al. Highlights • Intratumoral microbes have been revealed…
Britain’s NHS Is Dying — And It’s a Warning to the World The Tragic and Shocking Collapse of One of…
The reproducibility issues that haunt health-care AI. Health-care systems are rolling out artificial-intelligence tools for diagnosis and monitoring. But how…
Meta-analysis: Use of proton pump inhibitors and risk of gastric cancer in patients requiring gastric acid suppression Daniele Piovani et…
Dietary interventions for the treatment of inflammatory bowel diseases: an updated systematic review and meta-analysis Berkeley N. Limketkai et al.…
Microbiota Composition in Diverticular Disease: Implications for Therapy Antonio Tursi et al. Abstract: Gut microbiota (GM) composition and its imbalance…
Fauci responds to Musk’s Twitter attack and rates world’s COVID response Interview by Max Kozlov This month, Anthony Fauci will…
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly Paola Fugazzola et al. …
American Society for Gastrointestinal Endoscopy guideline on post-ERCP pancreatitis prevention strategies: summary and recommendations James L Buxbaum et al. LEGGI…
Microbiota of the Colonic Diverticula in the Complicated Form of Diverticulitis: A Case Report Dina Yarullina et al. Abstract Intestinal…
Altered Microbiota in Cirrhosis and Its Relationship to the Development of Infection Jasmohan S. Bajaj Figure 1 Changes in…
Da Sherlock Holmes al Dr House. Analogie fra pensiero medico e metodo investigativo CLAUDIO RAPEZZI (il prof. Rapezzi, Associato di…
Risk Heterogeneity and the Illusion of Waning Vaccine Efficacy Michael P. Fay et al. Critical scientific questions about COVID-19 vaccines…
Examining the Nocebo Effect in Trials of Neuromodulators for Use in Disorders of Gut-Brain Interaction Jeremy R. Glissen Brown et…
Tutti i problemi del primo farmaco anti-Alzheimer Aducanumab ha un prezzo eccessivo, tempi di approvazione inusuali e rapporti anomali tra…
2023 Should Be the Year We Admit the Internet Is a Failure With Hate, Rage, Bigotry, and Ignorance, the Internet’s…
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer John H. Strickler et al. BACKGROUND KRAS p.G12C mutation occurs in approximately 1 to 2%…
New Approaches to Chronic Hepatitis B Geoffrey Dusheiko et al. Chronic hepatitis B is caused by the hepatitis B virus…
What’s in a Number? Assessing the Burden of Diverticular Disease Mariam N. Hantouli et al. INTRODUCTION Annually, nearly 3 million…
Nearing 5,000 retractions: A review of 2022 Retractions of a given year’s publications as a percentage of papers published in…
RNA Sequencing as a Diagnostic Tool Shamika Ketkar et al. RNA sequencing (RNA-seq) is a new tool in…
Anxiety Disorders: A Review Kristin L. Szuhany; Naomi M. Simon Importance Anxiety disorders have a lifetime prevalence of approximately 34% in the…
Target trial emulation: applying principles of randomised trials to observational studies Anthony A Matthews et al. “using observational data…
2022’s Top 10 Gastroenterology Publications David A. Johnson, MD ‘Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis’ The WATERFALL study was an…
Efficacy and Safety of Drugs for Gastroparesis: Systematic Review and Network Meta-analysis. Maria Rosa Ingross et al. Background & Aims…
Replicability in the context of systematic reviews: A call for a framework with considerations regarding duplication, overlap, and intentionality Livia…
L-ornithine L-aspartate in acute treatment of severe hepatic encephalopathy: A double-blind randomized controlled trial Arpan Jainet al. Abstract Background and…
Contemporary Surgical Management of Pancreatic Necrosis Lydia R. Maurer, MD, MPH; Peter J. Fagenholz, MD Abstract Importance For decades, infected or symptomatic…
Clinical advances and ongoing trials of mRNA vaccines for cancer treatment Cathrine Lund Lorentzen et al. Summary Years of research…
The tumour immune microenvironment and microbiome of pancreatic intraductal papillary mucinous neoplasms Tommaso Pollini, et al Pancreatic intraductal papillary mucinous…
Obama: Internet indebolisce la democrazia Secondo l’ex presidente degli Stati Uniti servono nuove regole per contrastare la disinformazione in rete…
Comparison of Risk Scores for Lower Gastrointestinal Bleeding. A Systematic Review and Meta-analysis Majed Almaghrabi et al. Key Points Question Which risk…
Comparison of Society Guidelines for the Management and Surveillance of Pancreatic Cysts. A Review Hassan Aziz, et al Abstract Importance The identification…
Diagnosis and Management of Barrett’s Esophagus: An Updated ACG Guideline Shaheen, Nicholas J. et al. Abstract Barrett’s esophagus (BE) is…
Diagnostic accuracy of probe‑based confocal laser endomicroscopy and tissue sampling by endoscopic retrograde cholangiopancreatography in indeterminate biliary strictures: a meta‑analysis…
Restare aggiornati è complicato: ecco cosa il medico deve sapere LUCA DE FIORE “Se soffriamo un peso eccessivo per la…
Tolerating bad health research: the continuing scandal Stefania Pirosca et al. Abstract Background At the 2015 REWARD/EQUATOR conference on research…
Latest Cancer Research Suggests We’re Strikingly Close To Curing Cancer 12 Cancer Patients Were Just Cured by Dostarlimab: Here’s Why…
The COVID-NMA initiative A living mapping and living systematic review of Covid-19 trials COVID-NMA is an international research initiative supported…
COVID-19 Living Overview of Evidence repository is highly comprehensive and can be used as a single source for COVID-19 studies…
Concetti chiave in epidemiologia clinica: stima della probabilità pre-test Elenore Judy B. Uy Abstract Un’appropriata gestione medica dipende in gran…
Key concepts in clinical epidemiology: Estimating pre-test probability Elenore Judy B. Uy Abstract Appropriate medical management largely hinges on correctly…
Real-world data: a brief review of the methods, applications, challenges and opportunities Fang Liu, Panagiotakos Demosthenes Abstract Background: The increased adoption of…
Primary biliary cholangitis as a roadmap for the development of novel treatments of cholestatic liver diseases Frederik Nevens et al.…
Literature searches: what databases are available? Posted on 6th April 2021 by Izabel de Oliveira Many types of research require a…
A double-blind randomized placebo-controlled trial of albumin in outpatients with hepatic encephalopathy: HEAL study Andrew Fagan et al. Highlights •…
ROBERTA VILLA DA FNOMCEO: DOTTORE E’ VERO CHE? Guardando i dati globali sull’impatto della pandemia nazione per nazione salta…
Diverticular disease and cancer risk: More than a gut feeling Veronika Fedirko et al. Diverticular disease of the colon is…
Inflammatory bowel disease therapeutic strategies by modulation of the microbiota: how and when to introduce pre-, pro-, syn- or postbiotics?…
Association of Antisecretory Drugs with Upper Gastrointestinal Bleeding in Patients Using Oral Anticoagulants: A Systematic Review and Meta-Analysis Jacob E.…
Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation A Multinational Population-Based Cohort Study…
The microbiome-gut-brain axis in nutritional neuroscience Harriët Schellekens et al. ABSTRACT Emerging evidence is highlighting the microbiome as a key…
Advancing human gut microbiota research by considering gut transit time Nicola Procházková et al. Abstract Accumulating evidence indicates that gut…
A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis (PROCAP): a single-centre, patient-blinded, randomised controlled trial Ajith…
Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent Trisha Greenhalg et al. Abstract…
Responsible dissemination of health and medical research: some guidance points Raffaella Ravinetto and Jerome Amir Singh Ravinetto and Singh argue…
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies Mehdi Farokhnia et…
Rifaximin Effective for Multiple Symptoms in Irritable Bowel Syndrome With Diarrhea Colby Stong A 2-week course of rifaximin significantly improved…
Best way not to misuse p values is not to draw definitive conclusions about hypotheses David Trafimow et al. A recent…
Early Diagnosis and Prevention of Infections in Cirrhosis Anand V. Kulkarn et al. Abstract Strategies to prevent infection and improve…
Parola per parola, il formidabile discorso della giornalista che ha inchiodato Facebook Carole Cadwalladr. Presenta Riccardo Luna Quest’anno non sono…
Procalcitonin-guided reduction of antibiotic use in acute pancreatitis Gabriele Capurso, Enrique de-Madaria Acute pancreatitis is a challenging disease to treat,…
Mortality Risk Increased in Colonic Diverticular Disease: A Nationwide Cohort Study Raquel Cameron et al. Hightlights • WHAT IS KNOWN…
Ego Based Medicine Antonio Addis Ho il timore che tra le tante vittime del Covid-19 vada annoverata anche l’evidence based…
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis Enrique de-Madaria et al. Abstract BACKGROUND Early aggressive hydration is widely recommended…
Iscrivetevi alla nostra Newsletter per restare sempre aggiornato e in contatto col portale di EBGH. Uno strumento indispensabile per chi…
Likelihood ratio interpretation of the relative risk Suhail A R Doi et al. Interpreting diagnostic test results in medicine The likelihood…
Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis Elisa Pose, et al. Abstract…
Rifaximin and lubiprostone mitigate liver fibrosis development by repairing gut barrier function in diet–induced rat steatohepatitis Masahide Enomoto et al.…
Consensus Statement on Mandatory Measurements for Pancreatic Cancer Trials for Patients With Resectable or Borderline Resectable Disease (COMM-PACT-RB). A Systematic…
Rifaximin for the prevention and treatment of hepatic encephalopathy: a systematic review and meta-analysis of randomized clinical trials Harry Demetrios…
How COVID has deepened inequality — in six stark graphics Saima May Sidik The shock waves of the COVID-19 pandemic…
Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent Trisha Greenhalgh et al. Abstract Evidence-based…
Understanding the development and function of the gut microbiota in health and inflammation Deepak Selvakuma et al. Abstract The…
Why microbiome tests are currently of limited value for your clinical practice Patients usually ask for microbiome tests to manage…
Gut Microbiota Association with Diverticular Disease Pathogenesis and Progression: A Systematic Review Elisa Reitano et al. Abstract Introduction Growing evidence…
What is the difference between Probability and Likelihood? Priyanka Dandale Let us understand these two statistical terms in an easy…
Data Scientists Need to Know Just One Statistical Test Samuele Mazzanti After you read this, you will be able…
AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation Lin Chang et al. Background &…
AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea Anthony Lembo et al. BACKGROUND &…
Presunti colpevoli. Falsificazione e fabbricazione di dati nelle pubblicazioni scientifiche LUCA DE FIORE , ANTONIO ADDIS Riassunto. Le falsificazioni di risultati e…
Dalla medicina basata sulle evidenze alla decisione condivisa con il paziente: come gestire l’incertezza nella pratica clinica GIUSEPPE PARISI, PETER…
Comparison of Risk Scores for Lower Gastrointestinal Bleeding. A Systematic Review and Meta-analysis Majed Almaghrab et al. Key Points Question Which risk…
Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories…
Non sarà un’avventura Basare sulle prove la cura e le politiche sanitarie è la sola strada possibile. Di Marina Davoli e Luca De…
p-values: A Legacy of “Scientific Racism” A deeper look at the untold history of p-values and its legacy Raveena Jay…
PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer Andrea Cercek et al. Abstract BACKGROUND Neoadjuvant chemotherapy and radiation followed…
Gut Bacteria Linked to Stroke Severity, Risk Kelli Whitlock Burton Two new studies identifying strains of gut microbiota associated with…
Efficacy of Helicobacter pylori eradication therapy for functional dyspepsia: updated systematic review and meta-analysis Alexander C Ford et al. Abstract Objective Functional dyspepsia…
NEJM, other journals: provide more transparency about conflicts of interest or don’t publish conflicted articles Martin F. Shapiro and Sidney M. Wolfe…
Per Slow Medicine le prove sono indispensabili Tre esponenti del movimento per una medicina sobria, rispettosa e giusta intervengono nel…
Association of standardized radiology reporting and management of abdominal CT and MRI with diagnosis of pancreatic cancer Eleanor L Ormsby…
The best websites for researchers and academics Dr. Joe Bathelt The web is a treasure trove of resources that can…
Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions Nicolas Chapelle et al.…
Efficacy of a low FODMAP diet in irritable bowel syndrome: systematic review and network meta-analysis. Christopher J. Black et al.…
Pancreatic cancer surveillance and its ongoing challenges: is it time to refine our eligibility criteria? Thomas P Potjer Individuals at high…
Surgical Management of Gastric Cancer. A Review George Z. Li et al. Abstract Importance Surgery plays a critical role in the management…
Bill Gates explains “How to Prevent the Next Pandemic” His proposals for nipping infections in the bud are worth exploring…
Algorithm-based care versus usual care for the early recognition and management of complications after pancreatic resection in the Netherlands: an…
The Gut-Lymph Model Gives New Treatment Strategies for Organ Failure John A. Windsor et al. Organ Failure Remains an Unmet Global…
Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force Steven…
USPSTF Report on Aspirin for Primary Prevention Donald M. Lloyd-Jones As with many therapies in modern medicine, aspirin for the primary…
Risk of gastrointestinal bleeding with concomitant NOAC and glucocorticoid treatment Abstract Overview of: Holt A, Blanche P, Zareini B, et al. Gastrointestinal…
From info-desert to info-demic: the role of independent drug bulletins David Phizackerley James A Cave n the late 1950s and…
Two new oral antivirals for covid-19: ▼molnupiravir and ▼nirmatrelvir plus ritonavir Abstract This article is made freely available for…
Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis…
Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multi-center Inpatient Cirrhosis Cohort Jasmohan S Bajaj et al.…
Risk of Hepatocellular Carcinoma in Patients Treated With Entecavir vs Tenofovir for Chronic Hepatitis B A Korean Nationwide Cohort Study…
Acute-on-Chronic Liver Failure Clinical Guidelines Jasmohan S. Bajaj et al. In patients with cirrhosis and chronic liver disease, acute-on-chronic liver…
AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review William D. Chey DESCRIPTION: Irritable…
Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials Man Yang…
Surgical Management of Gastric Cancer: A Review George Z. Li et al. Abstract Importance Surgery plays a critical role in the management…
Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort…
Association Between Inflammatory Diets, Circulating Markers of Inflammation, and Risk of Diverticulitis Wenjie Ma et al. BACKGROUND & AIMS: Lifestyle…
Finding clues in unexpected places: detection of pancreatic cancer through the faecal microbiome Rachel Newsome AND Christian Jobin Pancreatic cancer…
A faecal microbiota signature with high specificity for pancreatic cancer Ece Karta et al. Abstract Background Recent evidence suggests a…
Efficacy of peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors for treatment of non-alcoholic fatty liver…
Self-expandable metal stents versus endoscopic balloon dilation for the treatment of strictures in Crohn’s disease (ProtDilat study): an open-label, multicentre,…
Understanding and Communicating Uncertainty in Achieving Diagnostic Excellence Maria R. Dahm, MA, PhD1; Carmel Crock, MBBS, BLit Uncertainty pervades the diagnostic process. In health care,…
Endoscopic management of subepithelial lesions including neuroendocrine neoplasms: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Pierre H Deprez et al.…
Oral Vancomycin Prophylaxis for Primary and Secondary Prevention of Clostridioides difficile Infection in Patients Treated with Systemic Antibiotic Therapy: A Systematic Review,…
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly Paola Fugazzola et al. Abstract…
Update on the management of gastrointestinal varices Umesha Boregowda et al. Abstract Cirrhosis of liver is a major problem in…
Baveno VII – Renewing consensus in portal hypertension Roberto de Franchis et al. Summary To expand on the work of…
Pancreatic cancer evolution and heterogeneity: integrating omics and clinical data Ashton A. Connor & Steven Gallinger Abstract Pancreatic ductal adenocarcinoma (PDAC),…
Efficacy of Helicobacter pylori eradication therapy for functional dyspepsia: updated systematic review and meta-analysis Alexander C Ford et al. Abstract Objective: Functional dyspepsia…
Single-arm clinical trials that supported FDA Accelerated Approvals have modest effect sizes and at high risk of bias Tatiane Bomfim…
Trent’anni di EBM: cosa è cambiato, cosa deve ancora cambiare Giulio Formoso Riassunto. In generale, medicina basata sulle prove e…
Density strips: visualisation of uncertainty in clinical data summaries and research findings Christopher J Weir , Adrian W Bowman Abstract…
Replicating scientific results is tough — but essential A high-profile replication study in cancer biology has obtained disappointing results. Scientists…
I Liberati’s principles dieci anni dopo ANTONIO ADDIS, LUCA DE FIORE Riassunto. A dieci anni dalla morte di Alessandro Liberati…
Hepatic encephalopathy: Thinking Beyond ammonia Hanna Blaney, M.D., M.P.H.,* and Sharon DeMorrow, Ph.D Hepatic encephalopathy (HE) is a syndrome of…
Gut Dysbiosis during COVID-19 and Potential Effect of Probiotics Yuan-Pin Hung et al. Abstract: Severe acute respiratory syndrome coronavirus 2…
Effects of Perioperative Probiotics and Synbiotics on Pancreaticoduodenectomy Patients: A Meta-Analysis of Randomized Controlled Trials Gang Tang et al. Post-pancreaticoduodenectomy…
Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American…
Oral Antiviral Treatments for COVID-19: Molnupiravir and Paxlovid Diana Ernst, RPh Molnupiravir Paxlovid Company Merck Pfizer Generic Name and Formulation…
‘Nocebo effect’: two-thirds of Covid jab reactions not caused by vaccine, study suggests US researchers show negative version of placebo…
Regole per delle scelte etiche Un itinerario formato da sei parole chiave Luciano Manicardi Regola L’etimologia della parola “regola” rinvia alla…
RAPID RECOMMENDATIONS A living WHO guideline on drugs for covid-19 Arnav Agarwal et al. https://doi.org/10.1136/bmj.m3379 PER SCARICARE LA GRAFICA INTERATTIVA…
Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Schalk W. et al. Main Recommendations 1 ESGE recommends the use…
The effect of probiotics on cognitive function across the human lifespan: A systematic review Jessica Eastwood et al. Highlights 30…
Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials Man Yang…
Efficacy and Safety of Nonantibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study) A Multicentre, Randomised, Open-label, Noninferiority Trial Mora-López, Laura…
State of Health in the EU: Italia Profilo della Sanità 2021 Punti salienti L’aspettativa di vita in Italia è tra…
ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease Katz, Philip O et al. Abstract Gastroesophageal reflux…
Association between pancreatic intraductal papillary mucinous neoplasms and extrapancreatic malignancies: A systematic review with meta-analysis Antonio Facciorusso et al. Abstract…
Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis Elisa Pose et al. ABSTRACT…
Rifaximin-a reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial Vishal C. Patel et al.…
Introducing NEJM Evidence Launching January 2022, NEJM Evidence, a new monthly digital journal from NEJM Group, presents innovative original research and…
Understand the real reasons reproducibility reform fails Lack of rigour is often blamed on pressure to publish. But ethnographers can…
Meta-Analysis of the Effect of Aspirin on Mortality in COVID-19 Husam M. Salah, et al. Repurposing of existing medications has…
Association of mortality and aspirin prescription for COVID-19 patients at the Veterans Health Administration Thomas F. Osborne et al. Abstract…
Global Incidence of Acute Pancreatitis Is Increasing Over Time: A Systematic Review and Meta-Analysis Jordan P. Iannuzzi et al. Background…
Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients Angélica Jayk Bernal et al. BACKGROUND New treatments are needed to…
Next-Generation Artificial Intelligence for Diagnosis From Predicting Diagnostic Labels to “Wayfinding” Julia Adler-Milstein et al. Improving the diagnostic process is…
Systematic review with meta-analysis: the effectiveness of either ustekinumab or vedolizumab in patients with Crohn’s disease refractory to anti-tumour necrosis…
Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: A large-scale multicenter cohort study Katsumasa…
Prognostic performance of the ‘DICA’ endoscopic classification and the ‘CODA’ score in predicting clinical outcomes of diverticular disease: an international,…
Trial sequential analysis: plain and simple Alessandro De Cassai et al. The use of trial sequential analysis (TSA) in the…
AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review Anne F Peery et al. Abstract Colonic diverticulitis…
Basic Probability Concepts for Data Science Probability helps to predict the unknown outcome of any event Zubair Hossian Motivation Probability…
Why we need to compare the rates of death between vaccinated and unvaccinated During a pandemic, you might see headlines like “Half…
A tale of two antiviral targets — and the COVID-19 drugs that bind them The FDA is considering authorizations for…
Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology Timothy M Errington et al. Abstract We conducted…
Systematic review and meta-analysis of observational studies on BD-IPMNS progression to malignancy lA.Balduzzi et al. Abstract Background The vast majority…
Reproducibility: expect less of the scientific paper Olavo B. Amaral & Kleber Neve Make science more reliable by placing the burden…
International Liver Cancer Association (ILCA) White Paper on Biomarker Development for Hepatocellular Carcinoma Amit G. Singal et al. Biomarkers are…
IMMEDIATE VERSUS POSTPONED INTERVENTION FOR INFECTED NECROTIZING PANCREATITIS Lotte Boxhoorn et al. Abstract Background: Infected necrotizing pancreatitis is a potentially lethal…
Drainage for Infected Pancreatic Necrosis — Is the Waiting the Hardest Part? Todd H. Baron, M.D. Acute necrotizing pancreatitis, which…
The h-index is no longer an effective correlate of scientific reputation Vladlen Koltun*, David Hafner Abstract The impact of individual…
Systemic Inflammation in Preclinical Ulcerative Colitis Daniel Bergemalm et al. BACKGROUND & AIMS: Preclinical ulcerative colitis is poorly defined. We…
Liver biopsy in the real world—reporting, expert concordance and correlation with a pragmatic clinical diagnosis Hannah P. Kim et al.…
How protein-based COVID vaccines could change the pandemic Jabs from Novavax and other biotech firms are coming. Scientists say they…
Come interpretare nella pratica il valore dell’ Hazard Ratio? gianfranco L’Hazard ratio (HR) è una delle misure che nella ricerca…
Managing Adult Acute and Acute-on-Chronic Liver Failure in the ICU Xuan Han, MD, MS; Andrew M. Davis, MD, MPH; William…
Would You Recommend Aspirin to This Patient for Primary Prevention of Atherosclerotic Cardiovascular Disease? Grand Rounds Discussion From Beth Israel…
Use of Confidence Intervals in Interpreting Nonstatistically Significant Results Alexander T. Hawkins, MD, MPH; Lauren R. Samuels, PhD The goal…
2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association Alice H. Lichtenstein et ali.…
Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis Ankit Chhoda et al. Abstract Background and…
Antiaging diets: Separating fact from fiction MITCHELL B. LEE et al. Caution around the fountain of youth The scientific and popular…
Management of disease-related malnutrition for patients being treated in hospital Philipp Schuetz et al. Abstract Disease-related malnutrition in adult patients…
Trial sequential analysis of EUS-guided gallbladder drainage versus percutaneous cholecystostomy in patients with acute cholecystitis AlessandroCucchetti et al. Abstract Background…
Regorafenib combined with transarterial chemoembolization for unresectable hepatocellular carcinoma: a real-world study Yue Han et al. Abstract Background The benefits…
Serologic response to coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis Atsushi…
Regorafenib combined with transarterial chemoembolization for unresectable hepatocellular carcinoma: a real-world study Yue Han et al. Abstract Background The benefits…
Molnupiravir vs. COVID-19: Will the drug live up to the hype? Katharine Lang In the search for effective COVID-19 treatments,…
How to Interpret and Use a Clinical Practice Guideline or RecommendationUsers’ Guides to the Medical Literature Romina Brignardello-Petersen,et al. Abstract Importance Clinicians…
ACG Clinical Guidelines: Management of Benign Anorectal Disorders Arnold Wald et al Abstract Benign anorectal disorders of structure and function…
JBIMANUAL FOR EVIDENCE SYNTHESIS April 2021 JBI Manual for Evidence Synthesis Welcome to the JBI Manual for Evidence Synthesis JBI…
TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial Rohit Loomba et al.…
Predictors of Opioid Prescribing for Non-Malignant Low Back Pain in an Italian Primary Care Setting Simona Cammarota et al. This…
Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease Fasiha Kanwal et al.…
REAL Centre. One year on Three myths about COVID-19 that the data proved wrong Data analysis (PDF version) • 23…
Covid and flu: what do the numbers tell us about morbidity and deaths? Much confusion has been seen in the…
Burden of compensated and decompensated cirrhosis: real world data from an Italian population-based cohort study S Cammarota et al. Abstract…
Gennaio 2021, Vol. 112, Suppl. 1 al N. 1 – Acquista l’articolo (vai sul sito de Il Pensiero Scientifico) Riassunto.…
Il medico dovrebbe sempre prescrivere le migliori terapie disponibili, ma aggiornarsi può essere complicato. Ogni anno, infatti, viene pubblicato un…
Nella pratica ambulatoriale e ospedaliera, la gastroenterologia e l’epatologia pediatrica rappresentano uno dei pilastri della formazione e dell’esperienza professionale, non…
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis Jason Hall…
Novel therapeutic targets for cholestatic and fatty liver disease Michael Trauner , Claudia Daniela Fuchs Abstract Cholestatic and non-alcoholic fatty liver…
Evidence-Based Management of Diverticular Disease: What’s New and What’s Missing? David R. Flum, • Thomas E. Read IT seems…
The promise of the gut microbiome as part of individualized treatment strategies Daniel A. Schupack, et al. Abstract Variability in…
Understanding one in 100,000 What does this tiny probability look like? Anthony B. Masters The EMA stated there was a plausible link…
Update on the management of sigmoid diverticulitis Mark H Hanna, Andreas M Kaiser Abstract Diverticular disease and diverticulitis are the…
Is Ivermectin For Covid-19 Based On Fraudulent Research? Part 4 The story of ivermectin for Covid-19 continues to get even…
Key concepts in clinical epidemiology: Stepped wedge trials Richard Hooper Abstract A stepped wedge trial evaluates an intervention that is…
AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in Inflammatory Bowel Diseases: Expert Review Sanjay K.…
The number needed to treat for net effect (NNTnet) as a metric for measuring combined benefits and harms Guowei Lia…
Systematic review with meta-analysis: The effects of non-steroidal anti-inflammatory drugs and anti-platelet therapy on the incidence and recurrence of hepatocellular…
Pancreatic Cancer A Review Wungki Park et al. IMPORTANCE Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer, with approximately…
Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis Alessandro Mantovan…
Bayesian interpretation of p values in clinical trials John Ferguson Abstract Commonly accepted statistical advice dictates that large-sample size…
Anti-Diabetic Medications for Type 2 Diabetics with Non-Alcoholic Fatty Liver Disease. Evidence from a Network Meta-Analysis of Randomised Controlled Trials…
TEN PAPERS FOR TEACHERS OF EVIDENCE-BASED MEDICINE AND HEALTH CARE. THE SICILY WORKSHOP 2019 David Nunan et al. Introduction A…
Management of Chronic Abdominal Distension and Bloating Brian E. Lacy et al. Abdominal bloating and distension are 2 of…
Perturbations in Gut Microbiota Composition in Psychiatric Disorders A Review and Meta-analysis Viktoriya L. Nikolova et al. IMPORTANCE Evidence of…
Social Media is Destroying a Generation of Young People — Especially Women If Anybody Else Did This to Young People,…
The next step in immorality: charging to create and cure disease Kamran Abbasi executive editor “charge patients to become sick…
The pandemic marks another grim milestone: 1 in 500 Americans have died of covid-19 By Dan Keatin , Akilah Johnson and…
Epidemiology, etiology and treatment of gastroparesis: real-world evidence from a large US national claims database Y. Ye et al. Background…
Newer Biologic and Small-Molecule Therapies for Inflammatory Bowel Disease Daniel C. Baumgart et al. Crohn’s disease and ulcerative colitis, together…
Flawed ivermectin preprint highlights challenges of COVID drug studies The study’s withdrawal from a preprint platform deals a blow to…
Covid-19: ivermectina alla prova Pubblicato martedì 21 Settembre 2021 Sulla base delle prove attuali, non c’è sufficiente certezza sull’efficacia e…
GRADE notes: How to use GRADE when there is “no” evidence? A case study of the expert evidence approach Reem…
GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings Linan Zeng et al. Abstract…
Hypothesis Tests Explained Angelica Lo Duca A quick overview of the concept of Hypothesis Testing, its classification in parametric and…
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised,…
Discontinuation of nucleot(s)ide analogue therapy in HBeAg-negative chronic hepatitis B: a meta-analysis Samuel Anthony Lachlan Hall et al. Abstract Background and…
A portal to the papers beyond paywalls QxMD Bets are a paywall has stopped you from reading a paper at…
The tangled history of mRNA vaccines Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic…
Odds != Probability Keith McNulty (Expert and Author in Applied Mathematics, Data Science, Statistics and Psychometrics. Find me on LinkedIn…
Evidence-Based Management of Hepatocellular Carcinoma: Systematic Review and Meta-analysis of Randomized Controlled Trials (2002–2020) Philipp K. Haber et al. Background…
Portal Hypertension and Ascites: Patient-and Population-centered Clinical Practice Guidelines by the Italian Association for the Study of the Liver (AISF)…
Global Spotlights A cardiovascular risk calculator to save millions of lives Mark Nicholls* It is a collaboration of about 200…
Development of a prioritisation tool for the updating of clinical guideline questions: the UpPriority Tool protocol Laura Martínez García et…
The UpPriority tool supported prioritization processes for updating clinical guideline questions Andrea Juliana Sanabria et al. Abstract Objective: We aim to…
Moving Beyond Guidelines—Use of Value-Based Preoperative Testing Niloofar Latifi, et al. In 2010, the Institute of Medicine estimated that the annual…
African languages to get more bespoke scientific terms Many words common to science have never been written in African languages.…
A Famous Honesty Researcher Is Retracting A Study Over Fake Data Renowned psychologist Dan Ariely literally wrote the book on…
Systematic review and network meta-analysis: efficacy of licensed drugs for abdominal bloating in irritable bowel syndrome with constipation Alfred D.…
Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA) A Randomized Clinical Trial Jeffry Florian et al. IMPORTANCE In…
The Microbiome as a Therapy in Pouchitis and Ulcerative Colitis Jean-Frédéric LeBlanc et al. Abstract The gut microbiome has been…
The Evidence Behind Robot-Assisted Abdominopelvic Surgery. A Systematic Review Naila H. Dhanani, eta al. Background: Use of robot-assisted surgery has…
Gut Microbiota Modulation and Fecal Transplantation: An Overview on Innovative Strategies for Hepatic Encephalopathy Treatment Ramzi Hassouneh and Jasmohan S.…
Coronavirus (COVID-19) Update: FDA Authorizes Drug for Treatment of COVID-19 Today, the U.S. Food and Drug Administration issued an emergency use…
Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19. A Meta-analysis The WHO Rapid Evidence Appraisal…
‘Too good to be true’: Doubts swirl around trial that saw 77% reduction in COVID-19 mortality Robert F. Service Science’s…
Progress in Pharmacotherapy for Obesity Susan Z. Yanovski et al. The obesity epidemic in the US continues unabated. The elevated…
Diagnosis and Treatment of Alcohol-Associated Liver Disease A Review Ashwani K. Singal, MD; Philippe Mathurin, MD IMPORTANCE Alcohol-associated liver disease…
Statistical Analysis of Biomedical Data — an Overview From p-values and regression to clustering and classification Sukanta Saha The last…
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis Ferenc Emil Mózes et…
Effects of Proton Pump Inhibitors on Glycemic Control and Incident Diabetes: A Systematic Review and Meta-Analysis Carol Chiung-Hui Peng et…
Therapeutic potential of microbial modulation in pancreatic cancer Vidhi Chandra, Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma…
Statistics: Are you Bayesian or Frequentist? The fastest way to diagnose your statistical alignment Cassie Kozyrkov What if I told…
How Britain Became the First Country in the World to Surrender to Covid This is What it Means to Be…
How to use likelihood ratios to interpret evidence from randomized trials Thomas V.Perneger Highlights • The likelihood ratio represents evidence from…
Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study…
AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia: Expert Review Peter S. Liang et al. DESCRIPTION: The purpose of…
ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections Colleen R. Kelly, et al. Clostridioides difficile infection occurs…
The Use of Rifaximin in Patients With Cirrhosis Paolo Caraceni et al. Abstract Rifaximin is an oral nonsystemic antibiotic with…
The Net Benefit of a treatment should take the correlation between benefits and harms into account Marc Buyse et al.…
Next-Generation Probiotics and Their Metabolites in COVID-19 Thomas Gautier et al. Abstract: Since December 2019, a global pandemic has been…
Widely Covered Paper on Ranitidine-Cancer Link Retracted Retraction Watch Staff A paper linking the use of a wildly popular drug…
The human gut microbiome and health inequities Katherine R. Amatoa et al. Individuals who are minoritized as a result of…
Simple Blood Test to Detect Colorectal Cancer Roxanne Nelson, RN, BSN In the future, a simple blood test could be…
Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia Patrícia O. Guimarães et al. BACKGROUND The efficacy and safety of tofacitinib, a…
Recruitment and Results Reporting of COVID-19 Randomized Clinical Trials Registered in the First 100 Days of the Pandemic Perrine Janiaud,…
Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021 Manon C. W.…
ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding Laine, Loren et al. Abstract We performed systematic reviews addressing predefined clinical…
ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury Chalasani, Naga P. et al. Abstract Idiosyncratic drug-induced liver…
Web-Based Educational Intervention for Patients With Uninvestigated Dyspepsia Referred for Upper Gastrointestinal Tract Endoscopy. A Randomized Clinical Trial Judith J. de…
Therapeutic potential of microbial modulation in pancreatic cancer Vidhi Chandra and Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC),…
Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at…
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome Dipesh H Vasant et al. Abstract Irritable bowel…
Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis Fen Liu et al. Abstract Background and Aim Previous…
A Microbiota-Directed Food Intervention for Undernourished Children Robert Y. Chen et al. Abstract BACKGROUND More than 30 million children worldwide…
Using Preprints in Evidence Synthesis: Commentary on experience during the COVID-19 pandemic Barbara Clyne et al. Introduction SARS-CoV-2, the virus…
HOW COVID BROKE THE EVIDENCE PIPELINE The pandemic stress-tested the way the world produces evidence — and revealed all the…
Probiotics: To Use or Not to Use? That Is the Question Max Schmulson Abstract This Editorial analyzes the paper by…
Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19 Markus F Neurath et al. Background: viruses in the…
Cara Amica, caro Amico, con le riaperture riapre anche il portale EVIDENCE BASED GASTROENTEROLOGY & HEPATOLOGY (EBGH). Abbiamo ripreso naturalmente…
Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials Cathrine Axfors, Andreas M.…
Bayesian Statistics of Efficacy of Pfizer-BioNTech COVID-19 Vaccine — part II Reproducing original results Bartek Skorulski Part II (this post)…
Bayesian Statistics of Efficacy of the Pfizer-BioNTech COVID-19 Vaccine — part I Vaccine Efficacy and Beta-binomial model Bartek Skorulski Posterior…
Mammals can breathe through their intestines By Nikk Ogasa On a good day, things exit through the anus. But in rodents…
The Gentlest of Introductions to Bayesian Data Analysis How to think in a natural way based on data Michał Oleszak…
The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Matthew J. Page et al. Abstract The Preferred Reporting…
Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021 Steven H. Woolf…
Evaluation of the Clinical Benefit of Cancer Drugs Submitted for Reimbursement Recommendation Decisions in Canada Daniel E. Meyers et al.…
Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions: letter Nicolas…
L’elogio dell’incertezza: una revisione sistematica living per valutare l’efficacia e la sicurezza dei trattamenti farmacologici per pazienti affetti da covid-19…
Meta-analysis of the Parkinson’s disease gut microbiome suggests alterations linked to intestinal inflammation Stefano Romano et al. Abstract The gut…
How to interpret p-value with COVID-19 data [No more confusion] How to find a p-value and ultimately reject the null…
Management of colonic diverticulitis Anne F Peery ABSTRACT Left sided colonic diverticulitis is a common and costly gastrointestinal disease…
Proton pump inhibitor on susceptibility to COVID-19 and its severity: a systematic review and meta-analysis Raymond Pranata et al. Abstract…
Role of Dietary Habits in the Prevention of Diverticular Disease Complications: A Systematic Review Marilia Carabotti et al. Abstract: Recent…
COVID vaccines and blood clots: five key questions As safety concerns delay the use of two COVID-19 vaccines, Nature looks at the…
Reporting only relative effect measures was potentially misleading: some good practices for improving the soundness of epidemiological results Precision in…
SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia Douglas B. Cines, M.D., and James B. Bussel, M.D. The coronavirus disease 2019 (Covid-19) pandemic…
Anticoagulation and In-Hospital Mortality From Coronavirus Disease 2019: A Systematic Review and Meta-Analysis Chatphatai Moonla, et al. Abstract Hypercoagulability in…
Impact of Antibiotic Resistance Genes in Gut Microbiome of Patients with Cirrhosis Amirhossein Shamsaddin et al. Abstract Background and aims…
Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome Florence Wong, M.B., B.S., M.D., et al for the…
Type 2 Diabetes Mellitus and COVID-19: A Narrative Review Salvatore Corrao et al. The pandemic of coronavirus disease (COVID-19), caused…
Evidence- based and mechanistic insights into exclusion diets for IBS Paul Moayyedi et al. Abstract Exclusion diets…
GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings Linan Zeng et al. Abstract…
