STENTING DELL’ESOFAGO: ULTIME LINEE GUIDA ESGE 2021

Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2021 Manon C. W. Spaander et al. Main recommendations Malignant disease 1 ESGE recommends placement of partially or fully covered self-expandable metal stents (SEMSs) for palliation of malignant dysphagia over laser therapy, photodynamic therapy, and esophageal bypass. Strong recommendation, high…

ULTIME LINEE GUIDA DELL’AMERICAN COLLEGE PER L’EMORRAGIA DIGESTIVA ALTA

ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding Laine, Loren  et al. Abstract We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency department to identify very-low-risk patients (e.g., Glasgow-Blatchford score = 0–1) who…

LINEE GUIDA DELL’AMERICAN COLLEGE PER DANNO EPATICO DA FARMACI

ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury Chalasani, Naga P. et al. Abstract Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology practices, and it can have multiple presentations, ranging from asymptomatic elevations in liver biochemistries to hepatocellular or cholestatic jaundice, liver failure, or chronic hepatitis. Antimicrobials, herbal and…

IL COLLOQUIO EDUCAZIONALE VIA WEB CON IL PAZIENTE DISPEPTICO RIDUCE LA RICHIESTA DI GASTROSCOPIE

Web-Based Educational Intervention for Patients With Uninvestigated Dyspepsia Referred for Upper Gastrointestinal Tract Endoscopy. A Randomized Clinical Trial Judith J. de Jong et al. Key PointsQuestion  Can dedicated health education for patients with uninvestigated dyspepsia reduce the number of upper gastrointestinal tract endoscopic procedures? Findings  This open-label, multicenter, clinical trial randomized 119 patients between health education or usual…

MODULAZIONE DEL MICROBIOTA: UNA POTENZIALE TERAPIA PER IL CANCRO DEL PANCREAS

Therapeutic potential of microbial modulation in pancreatic cancer Vidhi Chandra and Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is an aggressive disease with a poor prognosis.1 Surgery is the only potential curative treatment, but it is only possible in patients with early-stage disease, and most patients present with non-resectable disease.1 Even in patients who undergo…

RISCHIO DI CANCRO DOPO RISCONTRO DI ADENOMA: UNA OTTIMA META-ANALISI

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review and Meta-analysis Abhiram Duvvuri et al. BACKGROUND & AIMS: The risk of metachronous colorectal cancer (CRC) among patients with no adenomas, low-risk adenomas (LRAs), or high-risk adenomas (HRAs), detected at…