ACUTE-ON-ON CHRONIC : INSUFFICIENZA EPATICA IN CIRROSI DA VIRUS B. TENOFOVIR OD ENTECAVIR? ATTENZIONE: MEGLIO ENTECAVIR? UNA REVISIONE CON META-ANALISI DA “BMC Gastroenterology” (FREE)

Efficacy and safety of tenofovir disoproxil fumarate versus entecavir in the treatment of acute-on-chronic liver failure with hepatitis B: a systematic review and meta-analysis Neng Wang et al Abstract Background Oral nucleoside (acid) analogues (NAs) are recommended for patients with acute-on-chronic liver failure (ACLF) associated with hepatitis B virus (HBV-ACLF). The efficacy and safety of…

DIARREA DA ACIDI BILIARI. UNA OTTIMA REVIEW CON META-ANALISI. DA “AJG” (FREE)

The Efficacy of Treatments for Bile Acid Diarrhea: A Systematic Review and Meta-Analysis Dilmaghani Saam et al.  Introduction: Irritable bowel syndrome (IBS) affects up to 15% of the population. Among pathophysiological mechanisms for diarrhea-predominant IBS (IBS-D), one-third are due to bile acid (BA) diarrhea (BAD). The mainstay of treatment is bile acid sequestrants (BAS); yet…

GUIDA ALLA RICERCA DELLA LETTERATURA: UN MESSAGGIO DALLA COCHRANE PER LE RAPID REVIEWS! DA”BMJ EvidenceBased Medicine” (FREE)

Rapid reviews methods series: Guidance on literature search Irma Klerings et al. Abstract: This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process while maintaining systematic, transparent and reproducible methods. In this paper, we address considerations…

FARMACOTERAPIA PER LA DIPENDENZA DA ALCOL: OCCHIO A NALTREXONE ED AL ACAMPROSATO! UNA OTTIMA META-ANALISI. DA “JAMA”

Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis Melissa McPheeters et al Key Points Question  Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder? Findings  In this systematic review and meta-analysis that included 118 clinical trials and 20 976 participants, 50 mg/d of oral naltrexone and acamprosate were each associated with significantly improved…

CARCINOMA EPATOCELLULARE: LE NUOVE LINEE GUIDA PER LA TERAPIA CHIRURGICA DA AISF ED ALTRE SOCIETA’ DI SETTORE. DA” DIGESTIVE AND LIVER DISEASE” (PURTROPPO NON FREE)

Multidisciplinary Treatment of Hepatocellular Carcinoma in 2023: Italian practice Treatment Guidelines of the Italian Association for the Study of the Liver (AISF), Italian Association of Medical Oncology (AIOM), Italian Association of Hepato-Bilio-Pancreatic Surgery (AICEP), Italian Association of Hospital Gastroenterologists (AIGO), Italian Association of Radiology and Clinical Oncology (AIRO), Italian Society of Pathological Anatomy and Diagnostic…

ALLA RICERCA DELLA LETTERATURA PER LE REVISIONI RAPIDE: NUOVI SUGGERIMENTI DALLA COCHRANE! DA “BMJ EVIDENCE-BASED MEDICINE” (FREE)

Rapid reviews methods series: Guidance on literature search   Irma Klerings et al. Abstract This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process while maintaining systematic, transparent, and reproducible methods. In this paper, we…