REGORAFENIB DOPO TACE PER CARCINOMA EPATICO NON RESECABILE: UNO STUDIO DI REAL-WORLD EVIDENCE

EPATOLOGIA, EPATOLOGIA ONCOLOGICA, REAL WORLD EVIDENCE

Regorafenib combined with transarterial chemoembolization for unresectable hepatocellular carcinoma: a real-world study Yue Han et al. Abstract Background The benefits and tolerability of transarterial chemoembolization (TACE) combined with regorafenib as a second-line therapy has not been reported for unresectable hepatocellular carcinoma (HCC). This study aimed to explore the benefits and tolerability of TACE combined with…

LE MALATTIE INFIAMMATORIE IMMUNO-MEDIATE RISPONDONO MENO AL VACCINO A mRNA ANTI COVID-19. UNA OPPORTUNA META-ANALISI DA GASTROENTEROLOGY

COVID19 - EVIDENCE, REAL WORLD EVIDENCE

Serologic response to coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis Atsushi Sakuraba et al. BACKGROUND AND AIMS: Patients with immune-mediated inflammatory diseases (IMIDs) have an increased risk of COVID-19, primarily attributed to the use of immunosuppressive drugs such as glucocorticoids, which may attenuate the response to vaccines.…

REGORAFENIB E CHEMOEMBOLIZZAZIONE PER L’EPATOCARCINOMA NON RESECABILE. UNO STUDIO POSITIVO DI REAL WORLD EVIDENCE

DIAGNOSTICA PER IMMAGINI, EPATOLOGIA ONCOLOGICA, REAL WORLD EVIDENCE

Regorafenib combined with transarterial chemoembolization for unresectable hepatocellular carcinoma: a real-world study Yue Han et al. Abstract Background The benefits and tolerability of transarterial chemoembolization (TACE) combined with regorafenib as a second-line therapy has not been reported for unresectable hepatocellular carcinoma (HCC). This study aimed to explore the benefits and tolerability of TACE combined with…

OCCHIO AL MOLNUPIRAVIR PER OS COME ANTI COVID-19. QUALCHE RIFLESSIONE IN ATTESA DELLA APPROVAZIONE DA MEDICAL NEWS TODAY

COVID19 - EVIDENCE, GASTROENTEROLOGIA, GLOBAL HEALTH, MEDICI DI FAMIGLIA, MEDICINA INTERNA

Molnupiravir vs. COVID-19: Will the drug live up to the hype? Katharine Lang In the search for effective COVID-19 treatments, many drugs have failed to live up to their early promise. In a recent trial, seen as an important advance, the oral antiviral drug molnupiravir halved the risk of hospital admissions and deaths from COVID-19.…

COME INTERPRETARE UNA LINEA GUIDA ! DA JAMA

METODOLOGIA, REAL WORLD EVIDENCE

How to Interpret and Use a Clinical Practice Guideline or RecommendationUsers’ Guides to the Medical Literature Romina Brignardello-Petersen,et al. Abstract Importance  Clinicians may rely on recommendations from clinical practice guidelines for management of patients. Observations  A clinical practice guideline is a published statement that includes recommendations that are intended to optimize patient care. In the guideline development process,…

GESTIONE DELLE MALATTIE BENIGNE ANORETTALI: LE NUOVE LINEE GUIDA DALL’AMERICAN COLLEGE OF GASTROENTEROLOGY

CHIRURGIA, GASTROENTEROLOGIA, LINEE GUIDA EBM

ACG Clinical Guidelines: Management of Benign Anorectal Disorders Arnold Wald et al Abstract Benign anorectal disorders of structure and function are common in clinical practice. These guidelines summarize the preferred approach to the evaluation and management of defecation disorders, proctalgia syndromes, hemorrhoids, anal fissures, and fecal incontinence in adults and represent the official practice recommendations…