GESTIONE EBM DELLA DISTENSIONE E DEL GONFIORE ADDOMINALE

GASTROENTEROLOGIA, IBS, MALATTIA DIVERTICOLARE, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NUTRIZIONE

Management of Chronic Abdominal Distension and Bloating Brian E. Lacy et al.   Abdominal bloating and distension are 2 of the most commonly reported gastrointestinal symptoms. Abdominal bloating is characterized by symptoms of trapped gas, abdominal pressure, and fullness. Abdominal distension is defined as a measurable increase in abdominal girth. These symptoms frequently co-exist, although…

MICROBIOTA E DISORDINI PSICHIATRICI: UNA GRANDE REVISIONE CON META-ANALISI

MEDICINA DEI PROBIOTICI, MEDICINA INTERNA, METODOLOGIA

Perturbations in Gut Microbiota Composition in Psychiatric Disorders A Review and Meta-analysis Viktoriya L. Nikolova et al. IMPORTANCE Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions. OBJECTIVE…

ANCORA UN PASSO VERSO LA IMMORALITA’. DAL BMJ: ESITI SURROGATI E“ACCELERATED PATHWAYS” PER I FARMACI

INTERNATIONAL SNAPSHOTS, METODOLOGIA

The next step in immorality: charging to create and cure disease Kamran Abbasi executive editor “charge patients to become sick and be paid to help with treatment” Surrogate markers are seductive. In clinical trials and regulatory decisions, why not reach for something quick, convenient, and relatively cheap? Why stop patients receiving a treatment of plausible…

GASTROPARESI: EPIDEMIOLOGIA E TERAPIE DI REAL-WORLD EVIDENCE. UNO STUDIO SU GASTROENTEROLOGY DAL GRUPPO DI CAMILLERI

DISPEPSIA, GASTROENTEROLOGIA, REAL WORLD EVIDENCE

Epidemiology, etiology and treatment of gastroparesis: real-world evidence from a large US national claims database Y. Ye et al. Background & Aims While gastroparesis carries a considerable healthcare and patient burden, associated epidemiological data are limited. To provide new real-world evidence for gastroparesis, we estimated disease prevalence, and investigated patient demographics and disease etiology in…