ANTICOAGULANTI RIDUCONO LA MORTALITA PER COVID-19 OSPEDALIZZATI A DOSI PROFILATTICHE: LE DOSI TERAPEUTICHE AUMENTANO INVECE IL RISCHIO DI DECESSO. UNA META-ANALISI SU OLTRE 35.000 PAZIENTI

COVID19 - EVIDENCE, MEDICI DI FAMIGLIA, MEDICINA INTERNA

Anticoagulation and In-Hospital Mortality From Coronavirus Disease 2019: A Systematic Review and Meta-Analysis Chatphatai Moonla, et al. Abstract Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease severity during hospitalization but the reported survival benefits from anticoagulation (AC) vary among studies. We performed a literature research to estimate pooled odds ratios (ORs) of in-hospital mortality…

MICROBIOMA NEL CIRROTICO: LA RESISTENZA AGLI ANTIBIOTICI CRESCE NEL TEMPO MA NON CON LA RIFAXIMINA

CIRROSI EPATICA, EPATOLOGIA, GASTROENTEROLOGIA, MEDICINA DEI PROBIOTICI, MEDICINA INTERNA, Senza categoria

Impact of Antibiotic Resistance Genes in Gut Microbiome of Patients with Cirrhosis Amirhossein Shamsaddin et al. Abstract Background and aims Cirrhosis is associated with changes in intestinal microbiota that can lead to hepatic encephalopathy (HE) and infections, especially with antibiotic-resistant organisms. However, the impact of gut microbial antibiotic resistance gene (ARG) burden on clinical outcomes…

SINDROME EPATO-RENALE TYPE 1: TERLIPRESSINA EFFICACE CON ALBUMINA, MA OCCHIO ALLA INSUFFICIENZA RESPIRATORIA !

CIRROSI EPATICA, EPATOLOGIA, GASTROENTEROLOGIA

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome Florence Wong, M.B., B.S., M.D.,  et al for the CONFIRM Study Investigators* Abstract BACKGROUND The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome (HRS-1) in many parts of the world and is part of the clinical practice guidelines in Europe. METHODS We conducted…

DIABETE E COVID-19. UNA GRANDE REVISIONE DEL GRUPPO DI CORRAO (PA)

MEDICI DI FAMIGLIA, MEDICINA INTERNA, Senza categoria

Type 2 Diabetes Mellitus and COVID-19: A Narrative Review Salvatore Corrao et al. The pandemic of coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has involved more than one hundred million individuals, including more than two million deaths. Diabetes represents one of the most prevalent chronic conditions worldwide and significantly increases…

DIETE DI ESCLUSIONE E COLON IRRITABILE: UNA GRANDE REVISIONE EVIDENCE-BASED DI MOAYYEDI SU “NATURE GASTRO”

GASTROENTEROLOGIA, IBS, MALATTIA DIVERTICOLARE, MEDICINA DEI PROBIOTICI, MEDICINA INTERNA, NUTRIZIONE

Evidence- based and mechanistic insights into exclusion diets for IBS Paul Moayyedi et al.       Abstract Exclusion diets are becoming increasingly popular in the management of irritable bowel syndrome (IBS). Several mechanisms exist by which food items might cause gastrointestinal symptoms, such as direct osmotic effects of food in the gut lumen, changes…

GRADE EXPERT INVITANO AD UNA CORRETTA QUANTIFICAZIONE DELLA “CERTAINTY OF EVIDENCE” . LOOK AT THE FIGURES !

METODOLOGIA, REAL WORLD EVIDENCE

GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings Linan Zeng et al. Abstract Objective : To provide practical principles and examples to help GRADE users make optimal choices regarding their ratings of certainty of evidence using a minimally or partially contextualized approach. Study Design and Setting : Based on the…