DECONTAMINAZIONE BATTERICA PRIMA DI INTERVENTI CHIRURGICI PER LA MALATTIA DIVERTICOLARE

Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease Ulrich Wirth et al. ABSTRACT PURPOSE: There is an ongoing debate on whether or not to use oral antibiotic bowel decontamination in colorectal surgery, despite the numerous different regimens in terms of antibiotic substances and duration of application. As we routinely use oral…

EFFETTI COLLATERALI DEL TRAPIANTO FECALE: UNA REVISIONE IMPORTANTE

The Global Incidence of Faecal Microbiota Transplantation-related Adverse Events From 2000 to 2020 Cicilia Marcella et al. Abstract Background: Faecal microbiota transplantation (FMT) is an effective treatment in C. difficile infection (CDI) and is currently being investigated in other diseases. There is concern around the safety of FMT and that side effects or complications may be under-reported in…

PPI RIDUCONO EFFICACIA DI INFLIXIMAB NELLE IBD: UN’ OTTIMA META-ANALISI

The influence of proton pump inhibitor therapy on the outcome of infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies Thomas X Lu et al. Abstract Objective In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton…

LINEE GUIDA AGA 2021 DIVERTICOLITE

CLINICAL PRACTICE UPDATES AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review Anne F. Peery et al. Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for patients with this disease. The purpose of this Clinical Practice Update is to provide…

ED ILSISTEMA NERVOSO ENTERICO? UNA GRANDE REVIEW

Disorders of the enteric nervous system — a holistic view Beate Niesler et al Abstract The enteric nervous system (ENS) is the largest division of the peripheral nervous system and closely resembles components and functions of the central nervous system. Although the central role of the ENS in congenital enteric neuropathic disorders, including Hirschsprung disease…

NEI PAZIENTI RICOVERATI CON COVID REMDESIVIR, IROSSICLOROCHINA, LOPINAVIR ED INTERFERONE BETA NON RIDUCONO LA MORTALITA’.

In inpatients with COVID-19, none of remdesivir, hydroxychloroquine, lopinavir, or interferon b -1a differed from standard care for in-hospital mortality Pan H, Peto R, et al. Question: In adults hospitalized with coronavirus disease 2019 (COVID-19), what are the effects of 4 antiviral drugs compared with local standard care without the antivirals on in-hospital mortality? Design:…