STIPSI CRONICA DELL’ADULTO. PENSAVATE DI SAPERE TUTTO ? MEGLIO KIWI O PSYLLOGEL? SEGUITE LA NUOVE LINEE GUIDA DELLA ASSOCIAZIONE BRITANNICA DI NUTRIZIONE. DA”JHND” (FREE)

British Dietetic Association Guidelines for the Dietary Management of Chronic Constipation in Adults Eirini Dimidi et al. Abstract Background: Current clinical guidelines for chronic constipation offer limited dietary recommendations. The aim of this project was to develop the first comprehensive evidence-based dietary guidelines for the management of chronic constipation in adults. Methods: Four systematic reviews and meta-analyses…

COLON IRRITABILE. PENSAVATE DI SAPERE TUTTO, EH? OCCHIO ALLA NUOVA REVIEW EVIDENCE-BASED DA “ANNALS OF INTERNAL MEDICINE”

Irritable Bowel Syndrome  Katarina B. Greer, MD, MS, and Shahnaz Sultan, MD, MHSc Irritable bowel syndrome (IBS) is a common gastrointestinal disorder, with a prevalence of 4% to 10%. It is a chronic condition characterized by abdominal pain in conjunction with altered bowel habits, abdominal distention, or bloating. IBS can present with 3 different defecation patterns: IBS with constipation, IBS…

CAMRELIZUMAB+ RIVOCERANIB PERIOPERATIVO VERSUS CHIRURGIA NEL CARCINOMA EPATOCELLULARE RESECABILE. L’EDITORIALE. DA” THE LANCET” (FREE)

Perioperative camrelizumab plus rivoceranib versus surgery in resectable hepatocellular carcinoma Ahmed Kaseb ∙ Timothy M Pawlik Historically, hepatocellular carcinoma was deemed to be inherently drug resistant due to the presence of multidrug resistance genes that increased drug efflux and reduced drug uptake. For decades, multiple trials investigating systemic therapy for advanced hepatocellular carcinoma had failed to show clinical…

CAMRELIZUMAB + RIVOCERANIB PERIOPERATORIO MIGLIORA LA SOPRAVVIVENZA DEL CARCINOMA EPATOCELLULARE NEI PAZIENTI RESECABILI! UN TRIAL IMPORTANTE ! DA “THE LANCET” (FREE)

Perioperative camrelizumab plus rivoceranib versus surgery alone in patients with resectable hepatocellular carcinoma at intermediate or high risk of recurrence (CARES – 009): a randomised phase 2/3 trial Prof Zheng Wang, et al. Summary Background Surgical resection is the preferred curative approach for patients with early-stage hepatocellular carcinoma, but recurrence remains a major challenge. Consequently,…

IBD: GESTIONE DELLA GRAVIDANZA. ATTENZIONE ! CONSENSUS STATEMENT AMPIO DALLA FECONDAZIONE ALLA LATTAZIONE. DA “AMERICAN JOURNAL OF GASTROENTEROLOGY” (FREE)

Global Consensus Statement on the Management of Pregnancy in Inflammatory Bowel Disease Mahadevan, Uma et al. Introduction: Pregnancy can be a complex and risk filled event for women with inflammatory bowel disease (IBD). High-quality studies in this population are lacking, with limited data on medications approved to treat IBD during pregnancy. For patients, limited knowledge…

SFINTEROTOMIA PER PREVENIRE LA PANCREATITE POST-ERCP PRIMA DI INSERIMENTO PROTESI PER NEOPLASIA VIE BILIARI. ATTENZIONE! NON PIU’ NECESSARIA? UN IMPORTANTE TRIAL MULTICENTRICO DA “GUT”

Endoscopic sphincterotomy to prevent post-ERCP pancreatitis after self-expandable metal stent placement for distal malignant biliary obstruction (SPHINX): a multicentre, randomised controlled trial Anke M Onnekink et al. Abstract Background Endoscopic retrograde cholangiopancreatography (ERCP) with fully covered self-expandable metal stent (FCSEMS) placement is the preferred approach for biliary drainage in patients with suspected distal malignant biliary obstruction…