DIVERTICOLITE: UNA GUIDA PRATICA DALLA AGA. UNA REVISIONE TRA ESPERTI 2021

AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review Anne F Peery et al. Abstract Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for patients with this disease. The purpose of this Clinical Practice Update is to provide practical and…

BACK TO BASICS: UNA INTRODUZIONE ALLA COMPRENSIONE DELLA PROBABILITA’ (FREE)

Basic Probability Concepts for Data Science Probability helps to predict the unknown outcome of any event Zubair Hossian Motivation Probability is one of the most common terminologies, not only in mathematics but also in the real world. We use the word probability frequently. About seven years ago, I was in my secondary level of education and got…

PERCHE’ E’NECESSARIO CONFRONTARE IL TASSO DI DECESSI TRA VACCINATI E NON-VACCINATI: UNA RIFLESSIONE PER GLI AMICI NO-VAX DA “OUR WORLD IN DATA” (FREE)

Why we need to compare the rates of death between vaccinated and unvaccinated During a pandemic, you might see headlines like “Half of those who died from the virus were vaccinated”. It would be wrong to draw any conclusions about whether the vaccines are protecting people from the virus based on this headline. The headline is not…

I NUOVI AGENTI ANTIVIRALI PER IL COVID-19: UNA OTTIMA RIFLESSIONE DA “NATURE REVIEWS” (FREE)

A tale of two antiviral targets — and the COVID-19 drugs that bind them The FDA is considering authorizations for Pfizer’s paxlovid and Merck & Co.’s molnupiravir, the first two oral COVID-19 antivirals. Megan Cully COVID-19, for all of the problems it has created, has shown the unprecedented speed with which drug developers can move.…

IL GRAVE PROBLEMA DELLA RIPRODUCIBILITA’ (Reproducibility Project: Cancer Biology): SOLO IL 26% DEGLI ESPERIMENTI PRECLINICI IN ONCOLOGIA RISULTA RIPETIBILE (FREE)

Reproducibility in Cancer Biology: Challenges for assessing replicability in preclinical cancer biology Timothy M Errington et al. Abstract We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of preclinical research in cancer biology. The initial aim of the project was to repeat 193 experiments from 53 high-impact papers, using an approach in which the experimental…

IPMN (intraductal papillary mucinous neoplasms) DEL PANCREAS: UNA META-ANALISI ITALIANA DEGLI STUDI OSSERVAZIONALI CHE ATTENDEVAMO !

Systematic review and meta-analysis of observational studies on BD-IPMNS progression to malignancy lA.Balduzzi et al. Abstract Background The vast majority of presumed branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas are referred to a surveillance program due to the relatively low risk of malignancy. We aim to evaluate all available data from observational studies…