“GASTRIC OUTLET” OBSTRUCTION: MEGLIO LA GASTROENTEROANASTOMOSI VIA ECOENDO VS LA PROTESI METALLICA DUODENALE ! UN GRANDE TRIAL MULTICENTRICO RANDOMIZZATO. DA” LANCET GASTROENTEROLOGY & HEPATOLOGY”

Endoscopic ultrasonography-guided gastroenterostomy versus uncovered duodenal metal stenting for unresectable malignant gastric outlet obstruction (DRA-GOO): a multicentre randomised controlled trial Prof Anthony Yuen Bun Teoh et al. Summary Background Endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) is a novel endoscopic method to palliate malignant gastric outlet obstruction. We aimed to assess whether the use of EUS-GE with a…

MALATTIA DI CROHN. LA COMPOSIZIONE DEL MICROBIOMA ANNUNCIA LA COMPARSA DELLA MALATTIA NEI FAMILIARI! DA “GASTROENTEROLOGY! (FREE)

Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives Juan Antonio Raygoza Gara et al. Background & Aims The cause of Crohn’s disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control…

ATTENZIONE ! L’USO DEI BIOLOGICI PER IL CROHN: LE ULTIME LINEE GUIDA DEL GRUPPO IG-IBD! DA” Digestive and Liver Disease ” (FREE)

Use of biologics for the management of Crohn’s disease: IG-IBD clinical guidelines based on the GRADE methodology Fabio Salvatore Macaluso et al per Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD), Working panel, Review panel A cure for Crohn’s disease (CD), a chronic inflammatory disease of the gastrointestinal tract of unknown etiology, is…

EFFETTO DEL BIFIDOBACTERIUM SULLA GLICEMIA: UNA ATTENTA META-ANALISI NON EVIDENZIA RIDUZIONI NELL’UOMO. DA “Advances in Nutrition” (FREE)

The Effects of Bifidobacterium Probiotic Supplementation on Blood Glucose: A Systematic Review and Meta-Analysis of Animal Models and Clinical Evidence Emily P. Van Syoc et al. Abstract Probiotic supplementation is a potential therapeutic for metabolic diseases, including obesity, metabolic syndrome (MetS), and type 2 diabetes (T2D), but most studies deliver multiple species of bacteria in addition to…

PROBIOTICI E PROFILO LIPIDICO NELLA NASH: UNA OTTIMA “UMBRELLA REVIEW” CON META-ANALISI. DA “Systematic Reviews” (FREE)

Effects of gut microbial therapy on lipid profile in individuals with non-alcoholic fatty liver disease: an umbrella meta-analysis study Amirhossein Naghipour et al. Abstract Background Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, is closely associated with metabolic conditions such as obesity and diabetes mellitus, which significantly impact human health outcomes. The impaired…

IL TIMING PER LA COLECISTECTOMIA DOPO PANCREATITE BILIARE. L’INTERVENTO PRECOCE ENTRO 14 GG PUO’ COMPORTARE UN AUMENTO DELLA MORTALITA’. UN GRANDE STUDIO ITALIANO RETROSPETTIVO. DA “JAMA SURGERY”

Timing of Cholecystectomy After Moderate and Severe Acute Biliary Pancreatitis Marcello Di Martino et al. IMPORTANCE Considering the lack of equipoise regarding the timing of cholecystectomy in patients with moderately severe and severe acute biliary pancreatitis (ABP), it is critical to assess this issue. OBJECTIVE To assess the outcomes of early cholecystectomy (EC) in patients…