CARCINOMA EPATOCELLULARE: LE NUOVE LINEE GUIDA PER LA TERAPIA CHIRURGICA DA AISF ED ALTRE SOCIETA’ DI SETTORE. DA” DIGESTIVE AND LIVER DISEASE” (PURTROPPO NON FREE)

Multidisciplinary Treatment of Hepatocellular Carcinoma in 2023: Italian practice Treatment Guidelines of the Italian Association for the Study of the Liver (AISF), Italian Association of Medical Oncology (AIOM), Italian Association of Hepato-Bilio-Pancreatic Surgery (AICEP), Italian Association of Hospital Gastroenterologists (AIGO), Italian Association of Radiology and Clinical Oncology (AIRO), Italian Society of Pathological Anatomy and Diagnostic…

ALLA RICERCA DELLA LETTERATURA PER LE REVISIONI RAPIDE: NUOVI SUGGERIMENTI DALLA COCHRANE! DA “BMJ EVIDENCE-BASED MEDICINE” (FREE)

Rapid reviews methods series: Guidance on literature search   Irma Klerings et al. Abstract This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process while maintaining systematic, transparent, and reproducible methods. In this paper, we…

LA CHEMOPREVENZIONE DEL CANCRO COLORETTALE CON ASPIRINA FUNZIONA SOLO CON DOSI ELEVATE (500–1200 mg/day): UNA MAGNIFICA NETWORK META-ANALISI. DA “Br J Surg “.

Aspirin chemoprevention in colorectal cancer: network meta-analysis of low, moderate, and high doses Devansh Shah et al Abstract Background: Colorectal cancer is the third most common cancer, with nearly 2 million cases worldwide and just under 1 million deaths in 2020. Several trials have demonstrated that aspirin has the potential to reduce the incidence and/or recurrence…

I PROBIOTICI MIGLIORANO COLESTEROLO E TRIGLICERIDI NELLA STEATOSI EPATICA. UNA “UMBRELLA” META-ANALISI ! DA “Systematic Reviews” (FREE)

Efects of gut microbial therapy on lipid profile in individuals with non-alcoholic fatty liver disease: an umbrella meta-analysis study Amirhossein Naghipour et al. Background Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, is closely associated with metabolic conditions such as obesity and diabetes mellitus, which significantly impact human health outcomes. The impaired lipid…

APPENDICITE ACUTA! LA NUOVA TECNICA PER VIA ENDOSCOPICA HA LE STESSE PROBABILITA’ DI SUCCESSO DELLA APPENDICECTOMIA! UNA OTTIMA META-ANALISI DA UN GRUPPO ITALIANO. DA” SURGERY” (FREE).

Endoscopic retrograde appendicitis therapy versus appendectomy or antibiotics in the modern approach to uncomplicated acute appendicitis: A systematic review and meta-analysis Francesco Pata et al. Abstract Introduction: Endoscopic retrograde appendicitis therapy has been proposed as an alternative strategy for treating appendicitis, but debate exists on its role compared with conventional treatment. Methods: This systematic review was performed…

ATTENZIONE: GLI INIBITORI DELLA POMPA PROTONICA POTREBBERO ELEVARE IL RISCHIO CARDIOVASCOLARE E LA MORTALITA’ NEI PAZIENTI DIABETICI. DA”J Clin Endocrinol Metab “

Proton Pump Inhibitor Use and Risks of Cardiovascular Disease and Mortality in Patients With Type 2 Diabetes Tingting Geng et al. Abstract Context: Proton pump inhibitors (PPIs) are widely used drugs for gastric acid-related diseases and may affect the gut microbiome. Objective: We aimed to evaluate the associations of PPI use with risks of cardiovascular disease (CVD)…