Systematic review with meta-analysis: the effectiveness of either ustekinumab or vedolizumab in patients with Crohn’s disease refractory to anti-tumour necrosis factor Laurène Parrot, et al. Summary Background Ustekinumab and vedolizumab are commonly used after anti-tumour necrosis factor (TNF) failure in patients with Crohn’s disease (CD). No randomised controlled trial has compared these drugs. Aims To…
Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: A large-scale multicenter cohort study Katsumasa Kobayashi et al. Abstract Background and study aims: Prior studies have shown the effectiveness of endoscopic band ligation (EBL) and clipping for colonic diverticular hemorrhage (CDH) but have been small and conducted at single centers. Thus,…
Prognostic performance of the ‘DICA’ endoscopic classification and the ‘CODA’ score in predicting clinical outcomes of diverticular disease: an international, multicentre, prospective cohort study. Antonio Tursi et al. Abstract Objective To investigate the predictive value of the Diverticular Inflammation and Complication Assessment (DICA) classification and to develop and validate a combined endoscopic-clinical score predicting clinical outcomes…
Trial sequential analysis: plain and simple Alessandro De Cassai et al. The use of trial sequential analysis (TSA) in the medical literature is increasing in recent times. However, not all readers may be familiar with this statistical technique. This correspondence aims to provide readers with the essentials to understand and interpret TSA. Adequately conducted meta-analyses…
AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review Anne F Peery et al. Abstract Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for patients with this disease. The purpose of this Clinical Practice Update is to provide practical and…
Basic Probability Concepts for Data Science Probability helps to predict the unknown outcome of any event Zubair Hossian Motivation Probability is one of the most common terminologies, not only in mathematics but also in the real world. We use the word probability frequently. About seven years ago, I was in my secondary level of education and got…