JAK INIBITORI VS ANTI-TNF NELLE MALATTIE INFIAMMATORIE IMMUNOMEDIATE. CHI VINCE IN SICUREZZA? UNA REVISIONE SISTEMATICA CON META-ANALISI. DA” JAMA Netw Open” (FREE)

Comparative Safety of JAK Inhibitors vs TNF Antagonists in Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis Virginia Solitano et al. Abstract Importance: Janus kinase (JAK) inhibitors are highly effective medications for several immune-mediated inflammatory diseases (IMIDs). However, safety concerns have led to regulatory restrictions. Objective: To compare the risk of adverse events with JAK inhibitors vs…

PREVENZIONE DELLA PANCREATITE POST-ERCP. CRIOPREVENZIONE LOCALE? UN TRIAL MOLTO INTERESSANTE DAL GIAPPONE. DA “AMERICAN JOURNAL OF GASTROENTEROLOGY”

Local Postprocedural Cryoprevention Significantly Reduces the Incidence of Post-ERCP Pancreatitis: A Multicenter Randomized Controlled Trial Azuma, Shunjiro MD et al. INTRODUCTION: Postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is a common, potentially serious adverse event of ERCP. Although rectal nonsteroidal anti-inflammatory drugs are recommended for prevention, their use in Japan is limited due to dosage concerns.…

GASTROPARESI: LE LINEE GUIDA AGA EVIDENCE -BASED OTTOBRE 2025. DA “GASTROENTEROLOGY” (FREE)

AGA Clinical Practice Guideline on Management of Gastroparesis Kyle Staller et al. Abstract Background & Aims Gastroparesis is a complex gastric motility disorder characterized by nausea, vomiting, and other symptoms associated with a delay in gastric emptying in the absence of mechanical obstruction. Variations in diagnostic testing and limited effective treatments make caring for this patient…

BREAKING NEWS. BMJ COMMENTA LA NUOVA COMMISSIONE ITALIANA VACCINI !

Vaccine sceptics appointed to advise Italian government on immunisation Italy’s health minister has appointed two doctors with anti-vaccine views as advisers on immunisation policy, sending shockwaves through the country’s scientific community. The minister of health, Orazio Schillaci, formally reinstituted the National Immunisation Technical Advisory Group (NITAG) and appointed its members on 5 August.1 The most contentious…