L’INTESTINO COME “RESERVOIR” PER I VIRUS : LA LEZIONE DEL COVID-19

Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19 Markus F Neurath et al. Background: viruses in the healthy gut The gut microbiota is composed of bacteria, fungi and viruses.1–3 While the presence and composition of the bacteriome have been extensively studied in recent years, the ‘dark matter’ of microbiomes including viruses (viral microbiome…

IDROSSICLOROCHINA AUMENTA LA MORTALITA’ PER COVID-19: UNA META-ANALISI COLLABORATIVA DA “NATURE COMMUNICATIONS”

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials Cathrine Axfors, Andreas M. Schmitt. Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroquine and chloroquine on survival…

BAYES E VACCINO PFIZER-BIONTECH: UNA ATTENTA ANALISI SULLA EFFICACIA. DO YOU BAYES ? PARTE SECONDA

Bayesian Statistics of Efficacy of Pfizer-BioNTech COVID-19 Vaccine — part II Reproducing original results Bartek Skorulski Part II (this post) Reproducing statistics from the article Additional parameter θ Prior distribution of θ and an adjustment of occurrences Credible Interval for posterior Vaccine Efficacy COVID-19 occurrence in participants with and those without prior evidence of infection…

BAYES E VACCINO PFIZER-BIONTECH: UNA ATTENTA ANALISI SULLA EFFICACIA. DO YOU BAYES ? PARTE PRIMA

Bayesian Statistics of Efficacy of the Pfizer-BioNTech COVID-19 Vaccine — part I Vaccine Efficacy and Beta-binomial model Bartek Skorulski Posterior distribution with 95% Credible Interval: (90.8–97.9%) ,,,,,,,,,our results are that the vaccine efficacy is 95% with 95%-Credible Interval equal to (90.8–97.9%). You can get slightly different results but they should be very close. Those results…