SIETE STRESSATI? PRENDETE UN PROBIOTICO! UN TRIAL SULLO STRESS ACCADEMICO E Lacticaseibacillus rhamnosus. FINALMENTE UN ALTRO TRIAL BEN FATTO SUI PROBIOTICI. DA “nature npj biofilms and microbiomes” (FREE!)

GASTROENTEROLOGIA, IBS, MEDICI DI FAMIGLIA, MEDICINA DEI PROBIOTICI, NEWSLETTER

Probiotic-mediated modulation of gut microbiome in students exposed to academic stress: a randomized controlled trial Jorge Francisco Vázquez-Castellanos et al. Abstract Probiotics have been widely tested for their effect on mental well-being, albeit with heterogeneous outcomes. Direct and indirect effects through the gut microbiome might lie at the basis of these observations. Here, in a…

RIFAXIMINA NEL CIRROTICO. UN TRIAL SU 159 ASCITICI. RIFAXIMINA NON MIGLIORA SOPRAVVIVENZA E COMPLICAZIONI. O NO? OCCHIO ALLA ADERENZA ALLA TERAPIA. DA “J. OF HEPATOLOGY” (FREE!)

EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, NEWSLETTER

Effect of rifaximin in patients with severe cirrhosis and ascites: A randomized double-blind placebo-controlled clinical trial Thierry Thévenot et al. Highlights Standard of care for primary prophylaxis of spontaneous bacterial peritonitis currently relies on norfloxacin. 159 cirrhotic patients with ascites were enrolled in a double-blind, randomized trial. Participants received rifaximin or placebo for 12 months. Rifaximin…

LEGATURA VARICI: NON USATE DOPO GLI INIBITORI DELLA POMPA PROTONICA! UN OTTIMO TRIAL SEGNALA UN ECCESSO DI SIDE EFFECTS. DA “DIAGNOSTICS” (FREE!)

CIRROSI EPATICA, ENDOSCOPIA, EPATOLOGIA, GASTROENTEROLOGIA, NEWSLETTER

Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network Nisar Amin et al. Abstract Background: Proton pump inhibitors (PPIs) are frequently used after endoscopic variceal ligation (EVL) to reduce post-procedural bleeding, though studies have shown mixed results regarding their efficacy. While some suggest…

OSTRUZIONE BILIARE DA NEOPLASIA. MEGLIO IL DRENAGGIO DALLA COLECISTI OD IL DRENAGGIO DELLE VIE BILIARI ? SORPRESA: SONO EQUIVALENTI! UN GRANDE TRIAL INTERNAZIONALE. DA “ENDOSCOPY”

CHIRURGIA, DIAGNOSTICA PER IMMAGINI, ECOGRAFIA ED ECOENDOSCOPIA, ENDOSCOPIA, EPATOLOGIA ONCOLOGICA, NEWSLETTER, ONCOLOGIA, PANCREAS E VIE BILIARI

Endoscopic ultrasound-guided gallbladder versus bile duct drainage for first-line therapy of malignant biliary obstruction: international multicenter trial Benedetto Mangiavillano et al per il Biliary Therapeutic EUS Study Group Abstract Background Endoscopic ultrasound (EUS)-guided gallbladder drainage (GBD) and EUS-guided choledochoduodenostomy (CDS) with lumen-apposing metal stents are alternative approaches to endoscopic retrograde cholangiopancreatography. We compared EUS-GBD and EUS-CDS…

SEMAGLUTIDE MIGLIORA LA ISTOLOGIA NELLA MASH (METABOLIC ASSOCIATED STEATOHEPATITIS). IL TRIAL VS PLACEBO “ESSENCE”. RISULTATI PRELIMINARI SU 800 PAZIENTI A 2 ANNI. DA “NEJM” (NON FREE PURTROPPO)

ECOGRAFIA ED ECOENDOSCOPIA, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, NEWSLETTER, NUTRIZIONE

Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis  Arun J. Sanyal et al. for the ESSENCE Study Group Abstract Background Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Methods In this ongoing phase 3, multicenter, randomized, double-blind, placebo-controlled trial, we assigned 1197 patients with biopsy-defined…

CANCRO DEL RETTO. L’APPROCCIO CON ROBOT VS LAPAROSCOPIA. LO STUDIO “REAL” SU 1240 PAZIENTI. ATTENZIONE: LA CHIRURGIA ROBOTICA E’ SUPERIORE! DA”JAMA” (FREE!)

CHIRURGIA, GASTROENTEROLOGIA, NEWSLETTER, ONCOLOGIA

Robotic vs Laparoscopic Surgery for Middle and Low Rectal Cancer: The REAL Randomized Clinical Trial Qingyang Feng, MD et al. Key Points Question  Can the use of robotic surgery reduce the locoregional recurrence rate of middle and low rectal cancer compared with the use of laparoscopic surgery? Findings  In this randomized clinical trial including patients with middle…