EASL 2025: NOTIZIE PER L’EPATOLOGIA SELEZIONATE DA “THE LANCET” ! (FREE!)

EASL Congress 2025 Hugh Thomas  Undiagnosed liver fibrosis in Europe Undiagnosed liver fibrosis is common in the European adult population, primarily driven by metabolic risk factors and alcohol consumption, according to the prospective LIVERSCREEN cohort study. Isabel Graupera and colleagues enrolled 30 541 adults older than 40 years without known liver disease from nine European countries. Liver…

DOLORE DA PANCREATITE CRONICA: MEGLIO LA CHIRURGIA PRECOCE OD UN APPROCCIO ENDOSCOPICO? OCCHIO: SECONDO IL TRIAL ESCAPE NEL LUNGO TERMINE VINCE LA CHIRURGIA! DA: “JAMA SURGERY” (FREE!)

Long-Term Outcomes of Early Surgery vs Endoscopy First in Chronic Pancreatitis: Follow-Up Analysis of the ESCAPE Randomized Clinical Trial Charlotte L. van Veldhuisen, et al. Key Points Question  In patients with painful chronic pancreatitis with dilated pancreatic duct, does an early surgical approach result in improved clinical outcomes compared with an endoscopy-first approach? Findings  In this cohort study,…

MORBO DI CROHN DELL’ADULTO. LE ULTIME LINEE GUIDA AMERICANE EVIDENCE-BASED. SEMPRE 40 PAGINE ! MAGNIFICO! DA “AMERICAN JOURNAL OF GASTROENTEROLOGY” (FREE!)

ACG Clinical Guideline: Management of Crohn’s Disease in Adults Lichtenstein, Gary R. MD, FACG et al. Abstract Crohn’s disease (CD) is an idiopathic inflammatory disorder of unknown etiology with genetic, immunologic, and environmental influences. The incidence of CD has steadily increased over the past several decades. The diagnosis and treatment of patients with CD has…

COLITE ULCEROSA DELL’ADULTO: LE NUOVE LINEE GUIDA EVIDENCE-BASED AMERICANE. CORAGGIO: SOLO 40 PAGINE! DA “AMERICAN JOURNAL OF GASTROENTEROLOGY” (FREE!)

ACG Clinical Guideline Update: Ulcerative Colitis in Adults Rubin, David T. MD, FACG et al. Abstract Ulcerative colitis is an idiopathic inflammatory disorder of unknown etiology that seems to be rising in incidence and prevalence throughout the world. These guidelines were developed to indicate the preferred approach to the management of adult patients with ulcerative…

ISCHEMIA ACUTA DELLA MESENTERICA: UNA IMPORTANTE META-ANALISI ! EVIDENZA FINALE ANCORA LONTANA. DA “World Journal of Emergency Surgery” (FREE!)

Management of acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis Annika Reintam Blaser et al. Abstract Background Guidance on managing acute mesenteric ischaemia (AMI) is largely based on expert opinion and retrospective studies pooling different subtypes of AMI. In clinical practice, management strategy is often selected based on the patient’s severity of…

CANCRO FEGATO NON OPERABILE. NIVOLUMAB PIU’ IPILIMUMAB > LENVATINIB OR SORAFENIB IN PRIMA LINEA. UN TRIAL RANDOMIZZATO DA “THE LANCET” (FREE!)

Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial Thomas Yau et al. Summary Background Patients with unresectable hepatocellular carcinoma have a poor prognosis, and treatments with long-term benefits are needed. We report results from the preplanned interim analysis of the CheckMate 9DW…