EPATITE AUTOIMMUNE. LE NUOVE LINEE GUIDA INGLESI ! DA “GUT” (FREE!)

British Society of Gastroenterology guidelines for diagnosis and management of autoimmune hepatitis  Dermot Gleeson et al. Abstract Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. The last British Society of Gastroenterology (BSG) guideline for the management of AIH was published in 2011. Since…

COLONSCOPIA ASSOCIATA AD INTELLIGENZA ARTIFICIALE. LINEE GUIDA DELL’ AMERICAN GASTROENTEROLOGY ASSOCIATION. DA”GASTROENTEROLOGY” (FREE!)

AGA Living Clinical Practice Guideline on Computer-Aided Detection–Assisted Colonoscopy Shahnaz Sultan et al. Abstract Background & Aims This American Gastroenterological Association (AGA) guideline is intended to provide an overview of the evidence and support endoscopists and patients on the use of computer-aided detection (CADe) systems for the detection of colorectal polyps during colonoscopy. Methods A…

DIVERTICOLITE RICORRENTE: RESEZIONE DEL SIGMA O TERAPIA CONSERVATIVA? I RISULTATI DI UN OTTIMO TRIAL FINLANDESE. DA “JAMA SURGERY” (FREE!)

Sigmoid Resection vs Conservative Treatment After Diverticulitis Prespecified 4-Year Analysis of the LASER Randomized Clinical Trial Alexandre Santos, MD1; Panu Mentula, MD, PhD1; Tarja Pinta, MD, PhD2; et al Key Points Question  Does sigmoid resection offer sustained improvement in quality of life compared with long-term outcomes of conservative treatment for patients with recurring, complicated, or persistent painful diverticulitis? Findings  In this randomized clinical trial comparing elective…

COLANGITE BILIARE PRIMITIVA: AIFA APPROVA ELAFIBRANOR IN COMBINAZIONE CON URSO ! DA” GASTROINFO” (FREE!)

Colangite biliare primitiva: AIFA approva la rimborsabilità di elafibranor Redazione15 Aprile 2025 L’Agenzia Italiana del Farmaco (AIFA) ha annunciato l’imminente rimborsabilità del farmaco orfano elafibranor per il trattamento della colangite biliare primitiva. Questa decisione rappresenta un’importante opzione terapeutica aggiuntiva per una malattia epatica rara e progressiva che colpisce primariamente le donne tra i 45 e i 65 anni. La colangite…

MORBO DI CROHN. IL-23p19 VS USTEKINUMAB. UN’OTTIMA META-ANALISI DEI 5 TRIAL TESTA A TESTA. DA “AMERICAN JOURNAL OF GASTROENTEROLOGY” (FREE!)

IL-23p19 Antagonists vs Ustekinumab for Treatment of Crohn’s Disease: A Meta-Analysis of Randomized Controlled Trials Claudia Dziegielewsk et al. Abstract INTRODUCTION: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing interleukin (IL)-23p19 antagonists with ustekinumab, stratified by prior biologic exposure, in patients with moderate-to-severe Crohn’s disease (CD). METHODS: Through a systematic…

NUTRIZIONE ENTERALE NEL VOSTRO PAZIENTE IN OSPEDALE: IL RICOVERO INDUCE MALNUTRIZIONE. INTRODUCETE LA VALUTAZIONE NUTRIZIONALE ! UN’OTTIMA REVIEW EVIDENCE-BASED DAL NEJM (FREE!)

Enteral Nutrition in Hospitalized Adults Leah Gramlich, M.D., and Peggi Guenter, Ph.D., R.N. Enteral nutrition is defined as the provision of essential nutrients through an enteral tube to prevent or treat disease-related malnutrition in patients who are unable to consume adequate nutrients by mouth.1 The interplay of inadequate dietary intake and inflammation that characterizes disease-related…