ANTIBIOTICI IN PANCREATITE ACUTA. UN ALGORITMO BASATO SUI LIVELLI DI PROCALCITONINA. UN OTTIMO TRIAL DA “LANCET Gastroenterol Hepatol” .

CHIRURGIA, GASTROENTEROLOGIA, MEDICINA INTERNA, PANCREAS E VIE BILIARILascia un commento

A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis (PROCAP): a single-centre, patient-blinded, randomised controlled trial Ajith K Siriwardena et al. Abstract Background: Differentiating inflammation from bacterial infection in patients with acute pancreatitis can be difficult. Procalcitonin can distinguish infection from inflammation, and algorithms based on procalcitonin measurement can differentiate bacterial sepsis from…

DALLA EBM ALLA EBM + . E’ TEMPO DI UNA NUOVA EBM ! TRISHA GREENHALG COLPISCE ANCORA DA “BMJ EVIDENCE BASED MEDICINE” (FREE).

EBM IN EVIDENCE, METODOLOGIA, REAL WORLD EVIDENCELascia un commento

Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent Trisha Greenhalg et al. Abstract Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to the science of COVID-19. But these methods and tools were designed primarily to…

VERSO UNA DISSEMINAZIONE DELLE EVIDENZE PIU’ RESPONSABILE. DA “BMJ EVIDENCE BASED MEDICINE” (FREE). IL PROBLEMA DEI PRESS RELASE.

EBM IN EVIDENCE, GLOBAL HEALTH, METODOLOGIA, REAL WORLD EVIDENCELascia un commento

Responsible dissemination of health and medical research: some guidance points Raffaella Ravinetto and Jerome Amir Singh Ravinetto and Singh argue that better practices can be implemented when disseminating research findings through abstracts, preprints, peer-reviewed publications, press releases and social media Dissemination has been defined as ‘the targeted distribution of information and intervention materials to a…

ALDACTONE CONTRO LA MALATTIA DA ABUSO DI ALCOL. UN NUOVO APPROCCIO ? INTERESSANTE. DA SEGUIRE!

GASTROENTEROLOGIA, INTERNATIONAL SNAPSHOTS, MEDICI DI FAMIGLIA, MEDICINA INTERNALascia un commento

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies Mehdi Farokhnia et al. Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR) antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may represent a novel pharmacotherapy for alcohol use disorder (AUD). In this study, we tested the effects…

DA DDW 2022. RIFAXIMINA: POOLED ANALYSIS DI 2 TRIAL NELLA IBS-D.

GASTROENTEROLOGIA, IBS, MEDICI DI FAMIGLIA, MEDICINA INTERNALascia un commento

Rifaximin Effective for Multiple Symptoms in Irritable Bowel Syndrome With Diarrhea Colby Stong A 2-week course of rifaximin significantly improved multiple abdominal symptoms in patients with irritable bowel syndrome with diarrhea (IBS-D), according to study results presented at Digestive Disease Week (DDW), held from May 21 to 24, 2022, in San Diego, California, and virtually.…

UN CONSIGLIO: OCCHIO A COME USATE IL VALORE DELLA “P” ! DA “BMJ EVIDENCE BASED MEDICINE”.

METODOLOGIA, REAL WORLD EVIDENCELascia un commento

Best way not to misuse p values is not to draw definitive conclusions about hypotheses David Trafimow et al. A recent article in BMJ Evidence-Based Medicine asserted the following1 , ‘We begin by saying that p values themselves are not flawed. Rather, the use, misuse or abuse of p values in ways antithetical to rigorous scientific…