LA DILATAZIONE DEL WIRSUNG PEGGIORA LA PROGNOSI DELLE NEOPLASIE MUCINOSE INTRADUTTALI DEL PANCREAS (IPMN). UN IMPORTANTE STUDIO OSSERVAZIONALE GIAPPONESE SU 2.890 PAZIENTI. DA “Clinical Gastroenterology and Hepatology”

Clinical Outcomes of Intraductal Papillary Mucinous Neoplasms With Dilatation of the Main Pancreatic Duct. Tsuyoshi Hamada et al. BACKGROUND & AIMS: Dilatation of the main pancreatic duct (MPD) has been a surgical indication for intraductal papillary mucinous neoplasms (IPMNs). Few studies have investigated long-term outcomes of IPMNs with MPD dilatation. METHODS: Among 3,610 patients diagnosed with pancreatic…

LA INFEZIONE DA COVID-19 PROTEGGE DALLA REINFEZIONE. UNA GRANDE META-ANALISI DA “LANCET” VARIANTE PER VARIANTE (FREE)

Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis COVID-19 Forecasting Team Summary Background Understanding the level and characteristics of protection from past SARS-CoV-2 infection against subsequent re-infection, symptomatic COVID-19 disease, and severe disease is essential for predicting future potential disease burden, for designing policies that restrict travel or access to venues where…

ASPIRINA E RISCHIO CARDIOVASCOLARE. UNA NUOVA META-ANALISI PORTA IL RISCHIO DI EMORRAGIA DIGESTIVA A 21-98 CASI OGNI 10.000 PAZIENTI IN PIU’ RISPETTO AL CONTROLLO. DA “JACC: Advances” (FREE)

Aspirin With or Without Statin in Individuals Without Atherosclerotic Cardiovascular Disease Across Risk Categories Safi U. Khan et al   Abstract Background The effects of aspirin in adults without atherosclerotic cardiovascular disease (ASCVD), stratified by statin use across different ASCVD risks, remain uncertain. Objective To examine the effects of aspirin in adults without ASCVD, stratified by statin use across different…

RUOLO DEI BIOMARCATORI NELLA COLITE ULCEROSA. LE NUOVE LINEE GUIDA AGA. INSERITE ANCHE LA LATTOFERRINA FECALE! DA ” GASTROENTEROLOGY” (FREE)

AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis Siddharth Singh et al. Background & Aims Biomarkers are used frequently for noninvasive monitoring and treatment decision making in the management of patients with ulcerative colitis (UC). This American Gastroenterological Association (AGA) guideline is intended to support practitioners in decisions…

MALATTIA DI CROHN. LE LINEE GUIDA DEL GRUPPO IG-IBD APPENA USCITE! DA “Digestive and Liver Disease” (FREE)

Use of biologics for the management of Crohn’s disease: IG-IBD clinical guidelines based on the GRADE methodology FABIO MACALUSO ED Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) Abstract A cure for Crohn’s disease (CD), a chronic inflammatory disease of the gastrointestinal tract of unknown etiology, is not available, so patients require lifelong…

ONDANSETRON PER IL COLON IRRITABILE – DIARREA: IL TRIAL TRITON + META-ANALISI. BREAKING NEWS DA “ALIMENTARY PHARM & THERAP”

Randomised, Placebo-controlled Trial and Meta-analysis Show Benefit of Ondansetron for Irritable Bowel Syndrome with Diarrhoea: The TRITON Trial Gunn, David et al. Abstract Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS-D). Aim: To conduct a 12-week parallel group, randomised, double-blind, placebo-controlled trial of ondansetron 4mg o.d. (titrated up to 8mg t.d.s.) in…