I FARMACI ANTIDIABETICI PER LA STEATOSI NON ALCOLICA IN CORSO DI DIABETE: UNA META-ANALISI “NETWORK”

Anti-Diabetic Medications for Type 2 Diabetics with Non-Alcoholic Fatty Liver Disease. Evidence from a Network Meta-Analysis of Randomised Controlled Trials Cheng Han Ng, et al. Highlights • PPARγ agonists was ranked the best treatment for steatosis reduction. • SLGT2i was ranked the best treatment for fibrosis reduction • GLP-1RA and SGLT2i are superior for BMI reduction…

I MIGLIORI 10 PAPERS SULLA EBM (E PER INSEGNARLA!): IL WORKSHOP “SICILIA 2019” IN COLLABORAZIONE CON IL GRUPPO ITALIANO EBM

TEN PAPERS FOR TEACHERS OF EVIDENCE-BASED MEDICINE AND HEALTH CARE. THE SICILY WORKSHOP 2019 David Nunan et al. Introduction A previous article sought to signpost papers that were considered helpful when starting on the journey of practicing evidence-based medicine (EBM).1 The lead author was invited to run a workshop at the Eighth Conference of the…

GESTIONE EBM DELLA DISTENSIONE E DEL GONFIORE ADDOMINALE

Management of Chronic Abdominal Distension and Bloating Brian E. Lacy et al.   Abdominal bloating and distension are 2 of the most commonly reported gastrointestinal symptoms. Abdominal bloating is characterized by symptoms of trapped gas, abdominal pressure, and fullness. Abdominal distension is defined as a measurable increase in abdominal girth. These symptoms frequently co-exist, although…

MICROBIOTA E DISORDINI PSICHIATRICI: UNA GRANDE REVISIONE CON META-ANALISI

Perturbations in Gut Microbiota Composition in Psychiatric Disorders A Review and Meta-analysis Viktoriya L. Nikolova et al. IMPORTANCE Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions. OBJECTIVE…

I SOCIAL MEDIA STANNO DISTRUGGENDO UNA GENERAZIONE DI GIOVANI. UMAIR SU EUDAIMONIA&CO.

Social Media is Destroying a Generation of Young People — Especially Women If Anybody Else Did This to Young People, We’d Use Words Like Grooming, Abuse, and Pedophilia umair haque You see that chart above? It shows something that should deeply alarm you. Suicide rates have skyrocketed in young women and girls, since around 2009.…

ANCORA UN PASSO VERSO LA IMMORALITA’. DAL BMJ: ESITI SURROGATI E“ACCELERATED PATHWAYS” PER I FARMACI

The next step in immorality: charging to create and cure disease Kamran Abbasi executive editor “charge patients to become sick and be paid to help with treatment” Surrogate markers are seductive. In clinical trials and regulatory decisions, why not reach for something quick, convenient, and relatively cheap? Why stop patients receiving a treatment of plausible…