STANDARD CONSIGLIATO PER I TRIAL SUL CANCRO DEL PANCREAS , RESECABILE, O BORDERLINE RESECABILE. UN IMPORTANTE CONSENSUS STATEMENT DA “JAMA SURGERY” .

Consensus Statement on Mandatory Measurements for Pancreatic Cancer Trials for Patients With Resectable or Borderline Resectable Disease (COMM-PACT-RB). A Systematic Review and Delphi Consensus Statement. Esther N. Pijnappel et al. Abstract Importance  Pancreatic cancer is the third most common cause of cancer death; however, randomized clinical trials (RCTs) of survival in patients with resectable pancreatic cancer…

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IL COVID HA AUMENTATO TERRIBILMENTE LE DISEGUAGLIANZE. DA “NATURE” SEI GRAFICI IMPRESSIONANTI (FREE)

How COVID has deepened inequality — in six stark graphics Saima May Sidik The shock waves of the COVID-19 pandemic have reverberated throughout the world. But the latest data reveal that the burden of COVID and its aftermath does not rest equally. In six graphics, Nature details how the pandemic has worsened existing inequalities and exposed others…

ATTENZIONE, URGENTE ! OCCORRE PASSARE ALLA “EBM PLUS”, O “EBM+” DOPO LA EPIDEMIA (FREE).

Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent Trisha Greenhalgh et al. Abstract Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to the science of COVID-19. But these methods and tools were designed primarily to answer…

MICROBIOTA : QUALI FUNZIONI PER LA SALUTE? E PER LA INFIAMMAZIONE? UNA GRANDE REVIEW DA “FRONTLINE GASTROENTEROLOGY” (FREE)

Understanding the development and function of the gut microbiota in health and inflammation   Deepak Selvakuma et al. Abstract The gut microbiota is known to play an important role in maintaining gut health through a symbiotic relationship with the host. Altered gut microbiota is a common feature of several diseases of the gastrointestinal tract; however,…

LESS IS MORE : PERCHE’ I TEST SUL MICROBIOMA SONO DI POCA UTILITA’. DA “GUT MICROBIOTA AND HEALTH” (FREE)

Why microbiome tests are currently of limited value for your clinical practice Patients usually ask for microbiome tests to manage gut-related issues, to find out what type of diet or food supplement fits best and to get information about the risk of developing chronic diseases. But what kind of information do microbiome tests provide and…