COLITE MICROSCOPICA:ULTIME NOTIZIE SUL MANAGEMENT! da “CLINICAL GASTROENTEROLOGY & HEPATOLOGY”

Update on the Epidemiology and Management of Microscopic Colitis Anne F. Peery et al. Microscopic colitis is an inflammatory bowel disease that commonly presents with debilitating chronic watery diarrhea. Recent epidemiologic studies and randomized trials of therapeutics have improved the understanding of the disease. Medications, such as nonsteroidal antiinflammatories, proton pump inhibitors, and antidepressants, have…

“METROPANCREAS”: UNO SCORE SPETTACOLARE PER CHIARIRE QUANDO LA RESEZIONE PER CANCRO DEL PANCREAS E’ INUTILE. DA UNO STUDIO SU 1426 PAZIENTI PRESSO LE MIGLIORI PANCREAS UNIT DEL PAESE. DA”JAMA SURGERY” (FREE).

Futility of Up-Front Resection for Anatomically Resectable Pancreatic Cancer Stefano Crippa et al. Key PointsQuestion  What are the rates and factors associated with a futile up-front pancreatectomy in patients with anatomically resectable pancreatic ductal adenocarcinoma? Findings  In this observational study that included 1426 patients, the rate of futile pancreatectomy (death or disease recurrence within 6 months of the…

PROCINETICI: EXPERT REVIEW DALLE SOCIETA’ EUROPEA ED AMERICANA DI NEUROGASTROENTEROLOGIA E MOTILITA’

PROCINETICI: EFFICACIA E SICUREZZA DI 6 MOLECOLE. DA”NEUROGASTROENTEROLOGY&MOTILITY” Prokinetics-safety and efficacy: The European Society of Neurogastroenterology and Motility/The American Neurogastroenterology and Motility Society expert review Serhat Bor et al. Abstract Background: Prokinetics are a class of pharmacological drugs designed to improve gastrointestinal (GI) motility, either regionally or across the whole gut. Each drug has its…

EFFICACIA DEI PROBIOTICI NELLE IBD: UNA META-ANALISI AGGIORNATA (PER LA SOLA COLITE ULCEROSA: EVIDENZA CONCLUSIVA BASSA). DA “UEGJOURNAL” (FREE).

EFFICACY AND SAFETY OF PROBIOTICS IN IBD: AN OVERVIEW OF SYSTEMATIC REVIEWS AND UPDATED META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS   Maria Manuela Estevinho et al. Abstract Background and objective Probiotics show promise in inflammatory bowel disease (IBD), yet knowledge gaps persist. We performed an overview of systematic reviews and an updated metanalysis of randomized controlled…

SONO UTILI I PROBIOTICI NEL CIRROTICO ? UNA DISCRETA META-ANALISI PROPONE CALO DI AMMONIEMIA ED ENDOTOSSINEMIA (PIU’ TEST EPATICI). DA “European Journal of Pharmacology” (FREE).

Efficacy of probiotics on improvement of health outcomes in cirrhotic liver disease patients: A systematic review and meta-analysis of randomised controlled trials Unnah Leitner et al. Abstract Summary Liver cirrhosis is a chronic condition of the liver and is the 14th most common cause of death around the world; yet it remains an incurable disease. Probiotics…

IBD: E’ ORA DI CAMBIARE ROTTA NELLA TERAPIA ? IL RUOLO DELL’AMBIENTE. UN MAGNIFICO EDITORIALE DA”GASTROENTEROLOGY” (FREE)

It’s Time to Change Tack in IBD Treatment Marcel A. Behr ∙ Ildiko Mehes ∙ Charles N. Bernstein Contemporary reviews on the pathogenesis of inflammatory bowel diseases (IBDs; most commonly Crohn’s disease [CD] and ulcerative colitis [UC]) consistently invoke the etiologic triad of genetics, the environment, and the immune system (Figure 1).1–3 Yet the current treatment paradigm for IBDs exclusively seeks to dampen or…