I DUE NUOVI ANTIVIRALI ORALI PER IL COVID-19. UNA SCHEDA RIASSUNTIVA DA MPR

Oral Antiviral Treatments for COVID-19: Molnupiravir and Paxlovid Diana Ernst, RPh Molnupiravir Paxlovid Company Merck Pfizer Generic Name and Formulation Molnupiravir 200mg; capsules. Nirmatrelvir 150mg; ritonavir 100mg; tablets. Pharmacological Class Nucleoside analogue that inhibits SARS-CoV-2 replication by viral mutagenesis. SARS-CoV-2 main protease inhibitor + HIV-1 protease inhibitor and CYP3A inhibitor. Indication For the treatment of…

DUE TERZI DEGLI EFFETTI COLLATERALI DELLA DOSE DI VACCINI ANTI-COVID19 NON SONO DOVUTI ALLA INIEZIONE! L’EFFETTO “NOCEBO” IN UNA REVISIONE SU 12 TRIAL

‘Nocebo effect’: two-thirds of Covid jab reactions not caused by vaccine, study suggests US researchers show negative version of placebo effect behind many symptoms such as headaches and fatigue More than two-thirds of the common side-effects people experience after a Covid jab can be attributed to a negative version of the placebo effect rather than…

VERSO SCELTE ETICHE: 6 REGOLE PROPOSTE DAL PRIORE DI BOSE SU “FORWARD”(FREE)

Regole per delle scelte etiche Un itinerario formato da sei parole chiave Luciano Manicardi Regola L’etimologia della parola “regola” rinvia alla radice reg- che significa il “movimento che traccia una linea retta”. In questa nozione convivono una dimensione materiale e una morale. “La ‘retta’ rappresenta la norma; regula, è ‘lo strumento per tracciare la retta’ che fissa la regola. Ciò…

LINEE GUIDA WHO “LIVING” (AGGIORNATE A DICEMBRE 2021) SULLE TERAPIE ANTI-COVID 19. ANDATE SUL SITO DEL BMJ PER ACCEDERE ISTANTANEAMENTE ALLA GRAFICA INTERATTIVA FARMACO PER FARMACO! (FREE)

RAPID RECOMMENDATIONS A living WHO guideline on drugs for covid-19 Arnav Agarwal et al. https://doi.org/10.1136/bmj.m3379 PER SCARICARE LA GRAFICA INTERATTIVA ABSTRACT UPDATES This is a living guideline. It replaces earlier versions (4 September 2020, 20 November 2020, 17 December 2020, 31 March 2021, 6 July 2021, and 23 September 2021). The previous versions can be…

TERAPIE VIA ECOENDOSCOPIA: LE NUOVE LINEE GUIDA DELLA SOCIETA’ EUROPEA DI ENDOSCOPIA GASTROINTESTINALE (FREE)

Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Schalk W. et al. Main Recommendations 1 ESGE recommends the use of endoscopic ultrasound-guided biliary drainage (EUS-BD) over percutaneous transhepatic biliary drainage (PTBD) after failed endoscopic retrograde cholangiopancreatography (ERCP) in malignant distal biliary obstruction when local expertise is available. Strong recommendation, moderate quality evidence. 2 ESGE suggests…

L’USO DEI PROBIOTICI MIGLIORA LA FUNZIONE COGNITIVA ? UNA REVISIONE SISTEMATICA (FREE)

The effect of probiotics on cognitive function across the human lifespan: A systematic review Jessica Eastwood et al. Highlights 30 studies explored the effects of probiotic interventions on cognitive outcomes. The evidence is promising, particularly in clinical populations. Limitations within the literature are addressed. Abstract Recently the scientific community has seen a growing interest in…