BACK TO BAYES ! UN GRANDE INVITO ALLA STATISTICA DI BAYES. DA “LANCET”

EPATOLOGIA, GASTROENTEROLOGIA, METODOLOGIA, Senza categoria

Bayesian statistics for clinical research Ewan C Goligher, Anna Heath, Michael O Harhay Frequentist and Bayesian statistics represent two differing paradigms for the analysis of data. Frequentism became the dominant mode of statistical thinking in medical practice during the 20th century. The advent of modern computing has made Bayesian analysis increasingly accessible, enabling growing use…

STENOSI DEL TENUE DA CROHN: RESEZIONE, DILATAZIONE O TERAPIA ANTINFIAMMATORIA ? UN CASE REPORT CON OTTIMA REVISIONE DELLA LETTERATURA. DA “GASTROENTEROLOGY”

CHIRURGIA, GASTROENTEROLOGIA, IBD

Management of Small Bowel Crohn’s Disease Strictures: To cut, to stretch or to treat inflammation? Cathy Lu et al. on behalf of the Stenosis Therapy and Anti-Fibrosis Research Consortium This patient’s case history (void of protected health information) was discussed in a multidisciplinary meeting including adult gastroenterologists (C.L.; B.F.; F.R.), radiologists (M.B.; J.G.F), and a colorectal…

CISTI PANCREATICHE: UNA SPLENDIDA REVIEW DA “NEJM” (FREE)

CHIRURGIA, ECOGRAFIA ED ECOENDOSCOPIA, GASTROENTEROLOGIA, ONCOLOGIA, PANCREAS E VIE BILIARI, Senza categoria

Pancreatic Cysts Tamas A. Gonda, et al. Cystic lesions of the pancreas were once considered to be rare and of uncertain clinical significance, as reported in the Journal in 1934.1 Over subsequent decades, these lesions came to be recognized as more common than previously thought and potentially premalignant entities that warrant concern. Imaging studies have shown a prevalence…

LO STAGING CLINICO PER IL CARCINOMA PANCREATICO TENDE CLAMOROSAMENTE A SOTTOSTIMARE LO STADIO I E II PDAC. UNA IMPORTANTE LETTER DA “JAMA” SU 58.000 PAZIENTI. (FREE)

CHIRURGIA, GASTROENTEROLOGIA, ONCOLOGIA, PANCREAS E VIE BILIARI, Senza categoria

Accuracy of Clinical Staging in Early-Stage Pancreatic Ductal Adenocarcinoma Gerardo Perrotta et al.  The survival of patients with pancreatic ductal adenocarcinoma (PDAC) correlates with its pathologic stage, ranging from 3% in stage 4 (metastatic)1 to 83.7% in stage IA.2 Preoperative imaging, used in staging, underestimates lymph node involvement3 and may lead to inaccuracy, especially in early…

PROTESI BILIARE: SFINTEROTOMIA O NO? UNA BUONA META-ANALISI: AUMENTA IL RISCHIO DI EMORRAGIA? DA “GIE”

DIAGNOSTICA PER IMMAGINI, ECOGRAFIA ED ECOENDOSCOPIA, ENDOSCOPIA, GASTROENTEROLOGIA, Senza categoria

The addition of endoscopic sphincterotomy to biliary stent placement and its impact on the risk of adverse events: an updated meta-analysis of randomized controlled trials Otavio Cosendey Martins et al. Abstract Background and Aims Endoscopic sphincterotomy (ES) is not mandatory before biliary stenting. The impact of ES before biliary stent placement remains uncertain. Previous studies…

PROTESI BILIARE: SFINTEROTOMIA O NO? PIU’ RISCHI? UN OTTIMO EDITORIALE DA “GIE” (FREE). VAI ANCHE ALLA META-ANALISI IN CODA ALL’ARTICOLO.

DIAGNOSTICA PER IMMAGINI, ECOGRAFIA ED ECOENDOSCOPIA, ENDOSCOPIA, GASTROENTEROLOGIA, Senza categoria

Role of endoscopic sphincterotomy before biliary stent placement: More risks than benefits? Sahib Singh, MD Abbreviations ES (endoscopic sphincterotomy) PEP (post-ERCP pancreatitis) RCT (randomized controlled trial) SEMS (self-expandable metallic stent) Endoscopic sphincterotomy (ES), performed during ERCP, involves incision of the circumferential muscle within the sphincter of Oddi to facilitate biliary drainage. ES is indicated in patients with postsurgical biliary adverse events…