LA CONSENSUS ITALIANA SULLA GESTIONE DELLE RACCOLTE LIQUIDE DEL PANCREAS GUIDATA DA G.CAPURSO. PARTE PRIMA. DA “DIGESTIVE AND LIVER DISEASE”

The i-EUS consensus on the management of pancreatic fluid collections – Part 1 Gabriele Capurso et al. PER IL GRUPPO i-EUS Pancreatic fluid collections (PFCs), including pancreatic pseudocysts (PPs) and walled-off pancreatic necrosis (WON), are common complications of pancreatitis and pancreatic surgery. Historically, the treatment of these conditions has relied on surgical and radiological approaches;…

INTERVENTO CHIRURGICO PER ULCERA PEPTICA PERFORATA: LA MORTALITA’ (9.3%) E LA MORBIDITA’ (48.5%) A 30 GG RIMANGONO ELEVATE. UN GRANDE STUDIO INTERNAZIONALE DA “SURGICAL ENDOSCOPY”

Global 30-day morbidity and mortality of surgery for perforated peptic ulcer: GRACE study Mohamed Abouelazayem et al per il gruppo GRACE Abstract Background There is little international data on morbidity and mortality of surgery for perforated peptic ulcer (PPU). This study aimed to understand the global 30-day morbidity and mortality of patients undergoing surgery for…

COLITE ULCEROSA ACUTA. I TRIAL IN CORSO: COSA CI ASPETTA! DA “GUT”

Acute severe ulcerative colitis trials: the past, the present and the future Sailish Honap et al. Abstract Acute severe ulcerative colitis (ASUC), characterised by bloody diarrhoea and systemic inflammation, is associated with a significant risk of colectomy and a small risk of mortality. The landmark trial of cortisone in 1955 was pivotal for two reasons:…

RISANKIZUMAB VS USTEKINUMAB NEL CROHN. IL GRANDE TRIAL MULTICENTRICO “SEQUENCE”. NELLA REMISSIONE ENDOSCOPICA VINCE RISANKIZUMAB. DA “NEJM”

Risankizumab versus Ustekinumab for Moderate-to-Severe Crohn’s Disease L. Peyrin-Biroulet et al for the SEQUENCE Study Group. Abstract The efficacy and safety of risankizumab as compared with ustekinumab in patients with Crohn’s disease are unknown. METHODS In this phase 3b, multicenter, open-label, randomized, controlled trial with blinded assessment of end points, patients with moderate-to-severe Crohn’s disease…

CANCRO DELLO STOMACO E MICROBIOTA. UNA GRANDE REVISIONE ED UNO SGUARDO AL FUTURO. DA “GUT” (FREE)

Stomach microbiota in gastric cancer development and clinical implications Ruijie Zeng et al. Abstract Gastric cancer (GC) is one of the most common malignancies and a prominent cause of cancer mortality worldwide. A distinctive characteristic of GC is its intimate association with the commensal microbial community. Although Helicobacter pylori is widely recognised as an inciting factor…

PANCREATITE ACUTA SEVERA. NUTRIZIONE VIA SONDINO GASTRICO O DUODENALE ? NON SONO UGUALI PER SOLLIEVO DOLORE, INFEZIONI INDOTTE E DIARREA. UNA META-ANALISI DA ” BMC GASTROENTEROLOGY” (FREE)

Comparative safety assessment of nasogastric versus nasojejunal feeding initiated within 48 hours post-admission versus unrestricted timing in moderate or severe acute pancreatitis: a systematic review and meta-analysis Ming Wang et al.   Abstract Background The primary objective of this study is to comparatively assess the safety of nasogastric (NG) feeding versus nasojejunal (NJ) feeding in…